国际口腔医学杂志 ›› 2023, Vol. 50 ›› Issue (5): 613-617.doi: 10.7518/gjkq.2023073
摘要:
粪肠球菌是持续性根尖周炎中最主要的致病菌,含有多种毒力因子。宿主免疫防御能调动体内多种免疫细胞以及免疫分子来调控机体的炎症反应,可在粪肠球菌引起的持续性根尖周炎中发挥重要作用。然而,粪肠球菌在入侵机体的过程中可因多种逃逸及抵抗宿主免疫防御的机制,使其在宿主体内存活,进而造成组织损伤。本文对近年来粪肠球菌逃逸宿主免疫防御机制的研究进展作一综述,旨在从免疫角度探究粪肠球菌在根尖周组织中不易被清除机制,以期为持续性根尖周炎的防治提供新的思路。
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