Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (2): 241-243.doi: 10.3969/j.issn.1673-5749.2012.02.030

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Periodontitis of alveolar bone loss and T cells

Dai Lina, Zhang Ping.   

  1. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China
  • Received:2011-05-21 Revised:2011-10-18 Online:2012-03-01 Published:2012-03-01

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Abstract:

Periodontitis of alveolar bone loss is a common inflammatory destructive periodontal disease that leads to loss of the supporting structures of the teeth. T lymphocytes play an important role in the occurrence and development of periodontal disease. On one hand, T cells activated by antigens of periodontal pathogens are necessary for immune defense against periodontal pathogens. On the other hand, activated T cell is not only important regulator of activation or maturation of osteoclasts and bone resorption, but also the important damage cells in periodontal alveovar bone loss. This review elutidated the research progress on periodontitis of alveolar bone loss, T cells in the alveolar bone loss in periodontal diseases, T cells and interferon-γ on the role of osteoclasts.

Key words: alveolar bone loss, T lymphocyte, osteoclast


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