Int J Stomatol

Inter J Stomatol ›› 2017, Vol. 44 ›› Issue (1): 87-91.doi: 10.7518/gjkq.2017.01.018

• ·Reviews· • Previous Articles     Next Articles

The relationship between osteoclastic protein-tyrosine phosphatase and orthodontic treatment induced root resorption

Cui Yue, Jiang Huan, Hu Min.   

  1. Dept. of Orthodontics, Hospital of Stomatology, Jilin University, Changchun 130021, China
  • Received:2016-05-01 Online:2017-01-01 Published:2017-01-01

RichHTML

7

PDF (PC)

346

Abstract: Root resorption is a common complication of orthodontic treatment whose factors are very complicated. The processe of root resorption is similar to bone resorption. The cementoclast plays a main role in this process, and it is similar to the shape and function of osteoclasts. Osteoclastic protein-tyrosine phosphatase(PTP-oc) is mainly expressed in osteoclasts, and has a positive regulatory effect on osteoclasts. In this paper, the mechanism of PTP-oc is discussed, which provides a reference for the prevention and treatment of root resorption.

Key words: root resorption, osteoclastic protein-tyrosine phosphatase, mechanism of action

CLC Number: 

  • Q55

TrendMD: 
[1] Jiang RP, McDonald JP, Fu MK, Root resorption before and after orthodontic treatment: a clinical study of contributory factors[J]. Eur J Orthod, 2010, 32(6):693-697.
[2] Elhaddaoui R, Benyahia H, Azeroual MF, et al. Resorp-tion of maxillary incisors after orthodontic treat-ment—clinical study of risk factors[J]. Int Orthod, 2016, 14(1):48-64.
[3] 余丽霞, 何姝姝, 陈嵩. 全景及根尖片对正畸相关牙根吸收诊断准确性的研究[J]. 华西口腔医学杂志, 2012, 30(2):169-172. Yu LX, He SS, Chen S. Diagnostic accuracy of orthopantomogram and periapical film in evaluating root resorption associated with orthodontic force[J]. West Chin J Stomatol, 2012, 30(2):169-172.
[4] Amoui M, Baylink DJ, Tillman JB, et al. Expression of a structurally unique osteoclastic protein-tyrosine phosphatase is driven by an alternative intronic, cell type-specific promoter[J]. J Biol Chem, 2003, 278 (45):44273-44280.
[5] Amoui M, Suhr SM, Baylink DJ, et al. An osteo-clastic protein-tyrosine phosphatase may play a role in differentiation and activity of human monocytic U-937 cell-derived, osteoclast-like cells[J]. Am J Physiol Cell Physiol, 2004, 287(4):C874-C884.
[6] Sheng MH, Lau KH. Role of protein-tyrosine phos-phatases in regulation of osteoclastic activity[J]. Cell Mol Life Sci, 2009, 66(11/12):1946-1961.
[7] 姜欢. 正畸牙移动相关牙根吸收研究进展[J]. 口腔医学研究, 2011, 27(2):168-169. iang H. Research progress on tooth root resorption associated with orthodontic tooth movement[J]. J Oral Sci Res, 2011, 27(2):168-169.
[8] Aminoshariae A, Aminoshariae A, Valiathan M, et al. Association of genetic polymorphism and external apical root resorption: a systematic review [J]. Angle Orthod, 2016, 86(6):1042-1049.
[9] 李长霞, 李春雷, 朱双林, 等. 错类型对正畸治疗中牙根吸收影响的临床研究[J]. 实用口腔医学杂志, 2003, 19(4):336-338. Li CX, Li CL, Zhu SL, et al. Relationship between different types of malocclusion and root resorption during orthodontic treatment[J]. J Pract Stomatol, 2003, 19(4):336-338.
[10] Maués CP, do Nascimento RR, Vilella Ode V. Severe root resorption resulting from orthodontic treatment: prevalence and risk factors[J]. Dental Press J Orthod, 2015, 20(1):52-58.
[11] Kaku M, Sumi H, Shikata H, et al. Effects of pul-pectomyon the amount of root resorption during or-thodontic tooth movement[J]. J Endod, 2014, 40(3): 372-378.
[12] Lee YJ, Lee TY. External root resorption during orthodontic treatment in root-filled teeth and con-tralateral teeth with vital pulp: a clinical study of contributing factors[J]. Am J Orthod Dentofacial Orthop, 2016, 149(1):84-91.
[13] 白雪芹, 蒋红, 郝艳红, 等. Damon3自锁托槽与普通金属托槽对牙齿垂直移动影响的实验研究[J]. 口腔医学研究, 2008, 24(2):177-179. Bai XQ, Jiang H, Hao YH, et al. Comparative study on the alveolar bone remodeling during tooth in-trusion with damon3 self-ligating brackets and con-ventional brackets in beagle dogs[J]. J Oral Sci Res, 2008, 24(2):177-179.
[14] 刘筠, 郭宏铭. 自锁托槽与传统托槽导致正畸牙根吸收的锥形束CT比较[J]. 上海口腔医学, 2016, 25 (2):238-241. Liu Y, Guo HM. Comparison of root resorption be-tween self-ligating and conventional brackets using cone-beam CT[J]. Shanghai J Stomatol, 2016, 25(2): 238-241.
[15] Nakano T, Hotokezaka H, Hashimoto M, et al. Effects of different types of tooth movement and force ma-gnitudes on the amount of tooth movement and root resorption in rats[J]. Angle Orthodontist, 2014, 84 (6):1079-1085.
[16] Roscoe MG, Meira JB, Cattaneo PM. Association of orthodontic force system and root resorption: a sys-tematic review[J]. Am J Orthod Dentofacial Orthop, 2015, 147(5):610-626.
[17] Cuoghi OA, Aiello CA, Consolaro A, et al. Resorp-tion of roots of different dimension induced by dif-ferent types of forces[J]. Braz Oral Res, 2014, 28(1): 1-7.
[18] Samah A, Nora A, Nasir A, et al. The effect of ortho-dontic therapy on periodontal health: a review of the literature[J]. Int J Dent, 2014, 2014:585048.
[19] Oshiro T, Shibasaki Y, Martin TJ, et al. Immunoloca-lization of vacuolar-type H + -ATPase, cathepsin K, matrix metalloproteinase-9, and receptor activator of NF-κB ligand in odontoclasts during physiological root resorption of human deciduous teeth[J]. Anat Rec, 2001, 264(3):305-311.
[20] Diercke K, Kohl A, Lux CJ, et al. Compression of human primary cementoblasts leads to apoptosis: a possible cause of dental root resorption[J]. J Orofac Orthop, 2014, 75(6):430-445.
[21] Sheng MH, Wergedal JE, Mohan S, et al. Osteoac-tivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity[J]. FEBS Lett, 2008, 582(10):1451-1458.
[22] 卢嘉静, 葛振林. 正畸致牙根吸收的分子生物学研究进展[J]. 国际口腔医学杂志, 2008, 35(5):599- 601. Lu JJ, Ge ZL. Research process on the molecular mechanism of dental root resorption induced by or-thodontic treatment[J]. Int J Stomatol, 2008, 35(5): 599-601.
[23] Tonks NK. PTP1B: from the sidelines to the front lines[J]. FEBS Lett, 2003, 546(1):140-148.
[24] Hunter T, Karin M. The regulation of transcription by phosphorylation[J]. Cell, 1992, 70(3):375-387.
[25] Hendriks WJ, Elson A, Harroch S, et al. Protein tyrosine phosphatases: functional inferences from mouse models and human diseases[J]. FEBS J, 2008, 275(5):816-830.
[26] den Hertog J, Ostman A, Böhmer FD. Protein ty-rosine phosphatases: regulatory mechanisms[J]. FEBS J, 2008, 275(5):831-847.
[27] Yang JH, Amoui M, Strong DD, et al. Characteriza-tion and comparison of the intronic promoter of murine osteoclastic protein-tyrosine phosphatase, PTP-oc, with the human PTP-oc promoter[J]. Arch Biochem Biophys, 2007, 465(1):72-81.
[28] Wu LW, Baylink DJ, Lau KH. Molecular cloning and expression of a unique rabbit osteoclastic phos-photyrosyl phosphatase[J]. Biochem J, 1996, 316
(Pt 2):515-523.
[29] Aguiar RC, Yakushijin Y, Kharbanda S, et al. PTPROt: an alternatively spliced and developmentally re-gulated B-lymphoid phosphatase that promotes G0/G1 arrest[J]. Blood, 1999, 94(7):2403-2413.
[30] Soriano P, Montgomery C, Geske R, et al. Targeted disruption of the c-src proto-oncogene leads to osteo-petrosis in mice[J]. Cell, 1991(4):693-702.
[31] McHugh KP, Hodivala-Dilke K, Zheng MH, et al. Mice lacking beta3 integrins are osteosclerotic be-cause of dysfunctional osteoclasts[J]. J Clin Invest, 2000, 105(4):433-440.
[32] 覃立耿, 周兰岛, 庞广福, 等. RANK/RANKL/OPG系统与骨质疏松[J]. 右江民族医学院学报, 2014, 36(3):459-461. Qin LG, Zhou LD, Pang GF, et al. RANK/RANKL/OPG system and osteoporosis[J]. J Youjiang Med Univ Nat, 2014, 36(3):459-461.
[33] Hu Y, Liu W, Liu Z, et al. Receptor activator of nu-clear factor-kappa ligand, OPG, and IGF-I expression during orthodontically inducedinflammatory root resorption in the recombinant human growth hor-mone-treated rats[J]. Angle Orthod, 2015, 85(4): 562-569.
[34] Amoui M, Sheng MH, Chen ST, et al. A transmem-brane osteoclastic protein-tyrosine phosphatase re-gulates osteoclast activity in part by promoting os-teoclast survival through c-Src-dependent activation of NFkappaB and JNK2[J]. Arch Biochem Biophys, 2007, 463(1):47-59.
[35] Suhr SM, Pamula S, Baylink DJ, et al. Antisense oligodeoxynucleotide evidence that a unique os-teoclastic protein-tyrosine phosphatase is essential for osteoclastic resorption[J]. J Bone Miner Res, 2001, 16(10):1795-1803.
[36] Bastos JV, Côrtes MI, Silva JF, et al. A study of the interleukin-1 gene cluster polymorphisms and in-flammatory external root resorption in replanted permanent teeth[J]. Int Endod J, 2015, 48(9):878- 887.
[37] Lau KH, Stiffel V, Amoui M. An osteoclastic pro-tein-tyrosine phosphatase regulates the β3-integrin, syk, and shp1 signaling through respective src-dependent phosphorylation in osteoclasts[J]. Am J Physiol Cell Physiol, 2012, 302(11):C1676-C1686.
[38] Lau KH, Amoui M, Stiffel V, et al. An osteoclastic transmembrane protein-tyrosine phosphatase enhan-ces osteoclast activity in part by dephosphorylating Epha4 in osteoclasts[J]. J Cell Biochem, 2015, 116 (8):1785-1796.
[39] Hou J, Xia Y, Jiang R, et al. PTPRO plays a dual role in hepatic ischemia reperfusion injury through feedback activation of NF-κB[J]. J Hepatol, 2014, 60 (2):306-312.
[40] Haynie DT, Xue B. Superdomains in the protein structure hierarchy: the case of PTP-C2[J]. Protein Sci, 2015, 24(5):874-882.
（本文采编 王晴）
[1] Zeng Yanglin,Tan Xuelian,Song Dongzhe,Huang Dingming.. Research progress on diagnosis and treatment of root resorption [J]. Int J Stomatol, 2022, 49(5): 561-568.
[2] Wang Ningxiang,Liu Shuai,Lin Liangyuan,Wu Juan. Research progress on multiple idiopathic cervical root resorption [J]. Int J Stomatol, 2021, 48(3): 362-366.
[3] Zhou Yijie,Song Guangtai. Management of the intrusive luxation in young permanent teeth [J]. Int J Stomatol, 2021, 48(2): 135-140.
[4] Zhao Yujie,Guan Xiaoyan,Li Xiaolan,Chen Qijun,Wang Qian,Liu Jianguo. Research progress on macrophage polarization involved in the regulation of orthodontic tooth movement [J]. Int J Stomatol, 2020, 47(4): 478-483.
[5] Chen Xue,Li Shu. External cervical resorption [J]. Int J Stomatol, 2019, 46(5): 516-521.
[6] Xin Gao,Rongsheng Zeng. Research progress on osteoprotegerin in oral science [J]. Int J Stomatol, 2019, 46(3): 316-319.
[7] Xie Kexian, Wang Xiao, Li Yuangao, Zhang Ping.. Treatment of internal root resorption with calcific mass deposition [J]. Inter J Stomatol, 2015, 42(6): 628-630.
[8] Huang Jing1, Zhou Yi1, 2.. Research progress on tumor necrosis factor α and its inhibitors [J]. Inter J Stomatol, 2015, 42(1): 63-68.
[9] Ren Hongyu, Chen Xin. Comparison of cone-beam computed tomography with different voxel resolutions and panoramic imaging for detecting simulated apical root resorption [J]. Inter J Stomatol, 2014, 41(5): 514-517.
[10] Liu Lin1, Wang Shengyu2, Yuan Xiaoping1.. Effects of parathyroid hormone and parathyroid hormone related protein in the related cells of tooth repair [J]. Inter J Stomatol, 2012, 39(3): 376-379.
[11] Bao Xingfu, Hu Min.. Research progress on mechanisms and regulations of bone resorption in orthodontic tooth movement [J]. Inter J Stomatol, 2012, 39(2): 187-189.
[12] Lu Shijun1, Wang Lin2, Wang Zhendong2.. Progress of anterior teeth intrusion in deep overbite treatment [J]. Inter J Stomatol, 2011, 38(6): 674-676.
[13] MA Lan, SONG Guang-tai. Correlation of permanent successor with physiological root resorption of primary [J]. Inter J Stomatol, 2010, 37(3): 284-284～286.
[14] XIE Ni -na, SONG Guang-tai . Research progress of physiological root resorption mechanism of deciduous teeth[J]. Inter J Stomatol, 2010, 37(3): 306-306～309.
[15] XIE Ni-na, XU Wen-an, SONG Guang-tai, HAN Jian-guo. . Expression and significance of tartrate-resistant acid phosphatase during the stage of physiological root resorption of rabbits [J]. Inter J Stomatol, 2010, 37(01): 7-9.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[7] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 458 -460 .
[8] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 452 -454 .
[9] . [J]. Inter J Stomatol, 2008, 35(S1): .
[10] . [J]. Inter J Stomatol, 2008, 35(S1): .