国际口腔医学杂志 ›› 2018, Vol. 45 ›› Issue (1): 42-45.doi: 10.7518/gjkq.2018.01.008

• 综述 • 上一篇    下一篇

单链DNA结合蛋白1的研究进展

曾祥林, 王代友   

  1. 广西医科大学附属口腔医院口腔颌面外科 南宁 530021
  • 收稿日期:2017-05-22 修回日期:2017-10-15 出版日期:2018-01-01 发布日期:2018-01-01
  • 通讯作者: 王代友,教授,博士,Email:wangdaiyou@sina.com
  • 作者简介:曾祥林,硕士,Email:zengxianglinhx@sina.com
  • 基金资助:
    广西自然科学基金(2014GXNSFDA118022)

Research progress on single-stranded DNA-binding protein 1

Zeng Xianglin, Wang Daiyou   

  1. Dept. of Oral and Maxillofacial Surgery, College of Stomatology, Guangxi Medical University, Nanning 530021, China
  • Received:2017-05-22 Revised:2017-10-15 Online:2018-01-01 Published:2018-01-01
  • Supported by:
    This study was supported by Natural Science Foundation of The Guangxi Zhuang Autonomous Region (2014GXNSF-DA118022).

摘要: 单链DNA结合蛋白(SSB)1是在人类身上新发现的一种单链DNA结合蛋白,它通过参与各种DNA损伤修复过程维持基因的完整性与稳定性。这一重大发现为各种DNA损伤修复机制提供了新的见解。本文就SSB1相关结构及功能的研究进展进行综述。

关键词: 单链DNA结合蛋白1, 结构, 功能

Abstract: Single-stranded DNA-binding protein (SSB) 1 is a newly discovered SSB in humans. Given its involvement in DNA damage repair, SSB1 is critical for genomic integrity and stability. This significant discovery provides new insights into the mechanism of DNA damage repair. In this study, we reviewed the research progress on the structure and function of SSB1.

Key words: single-stranded DNA-binding protein 1, structure, function

中图分类号: 

  • Q754
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