Int J Stomatol

Inter J Stomatol ›› 2013, Vol. 40 ›› Issue (4): 550-552.doi: 10.7518/gjkq.2013.04.040

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Osteoblasts and the regulations of early responses to stress

Li Xin, Liu Heng, Sun Huiqiang.   

  1. Dept. of Prosthodontics, Hospital of Stomatology, Shandong University; Shandong Provincial Key Laboratory of Oral Biomedicine, Jinan 250012, China
  • Received:2012-08-23 Revised:2013-04-08 Online:2013-07-01 Published:2013-07-01

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Abstract:

Mechanical stress plays an important role in the remodeling of bone. Stress can regulate the differentiation and function of osteoblasts and osteoclasts through a variety of signaling pathways, so as to achieve a balance of bone metabolism. Osteoblasts are regarded as the main cells participating in the formation of alveolar bone in stomatology. Early responses of osteoblasts to mechanical stress mainly depend on: Cell-cell communication, gap junctions, calcium ion signal pathway and fluid shear stress, etc.. This article summarized the early responses of osteoblasts to mechanical loading.

Key words: osteoblast, gap junction, cell-cell communication, calcium ion signal channel


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[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
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[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[7] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 458 -460 .
[8] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 452 -454 .
[9] . [J]. Inter J Stomatol, 2008, 35(S1): .
[10] . [J]. Inter J Stomatol, 2008, 35(S1): .