Int J Stomatol ›› 2025, Vol. 52 ›› Issue (4): 466-472.doi: 10.7518/gjkq.2025038

• Cariology and Endodontics • Previous Articles     Next Articles

Progress in research on natural plant extracts as root canal irritants

Bin Qi(),Haiming Xu,Zhishan Lu()   

  1. Dept. of Endodontics, Yantai Stomatological Hospital Affiliated to Binzhou Medical College, Yantai 264008, China
  • Received:2024-01-31 Revised:2024-08-23 Online:2025-07-01 Published:2025-06-20
  • Contact: Zhishan Lu E-mail:qibinchn@163.com;dentlzs@163.com

Abstract:

“Infection control” is the core of root canal treatment. Owing to the intricate three-dimensional structure of the root canal system, relying on mechanical preparation methods cannot achieve thorough root canal debridement and often requires a combination of chemical preparation methods, such as root canal irrigation. However, chemical root canal irritants have drawbacks, such as cytotoxicity and adverse effects on the physicochemical properties of dentin. Natural plant extracts as root canal irritants have attracted considerable interest because they are widely available and have low toxicity, low cost, and antibacterial properties. This article provides a review of the classification of natural plant extracts, in vitro and in vivo studies, and novel strategies for using natural plant extracts as root canal irritants, providing a refe-rence for their clinical application.

Key words: root canal therapy, root canal irrigants, natural plant extracts

CLC Number: 

  • R781.05

TrendMD: 
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