Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (6): 814-817.doi: 10.3969/j.issn.1673-5749.2012.06.030

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Treatment of infantile haemangioma in the head and neck region with propranolol

Wang Weicai, Hou Jinsong.   

  1. Dept. of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China
  • Received:2012-01-15 Revised:2012-08-22 Online:2012-11-01 Published:2012-11-01

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Abstract:

Infantile haemangioma is a kind of the commonest childhood tumours and frequently occured in the head and neck region. They have a self-limiting course, but approximately 10% lesions require various treatment. Current clinical treatment include systemic or intralesional corticosteroids, vincristine, alpha-interferon, sclerotherapy, laser, or comprehensive of these therapies. Recent reports have highlighted the impressive efficacy of propranolol in treating rapidly proliferating haemangioma. This review focuses on the molecule mechanism of propranolol to treatment of haemangioma, clinical application and adverse respones.

Key words: propranolol, infantile haemangioma, head and neck


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