Int J Stomatol

Inter J Stomatol ›› 2011, Vol. 38 ›› Issue (4): 436-438.doi: 10.3969/j.issn.1673-5749.2011.04.019

Previous Articles     Next Articles

Research progress on ubiquitination of hypoxia inducible factor-1

Zou Haixiao, Zhao Yifang, Jia Jun.   

  1. The State Key Laboratory Breeding Base of Basic Science of Stomatology（Hubei -MOST） & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2009-11-11 Revised:2011-01-11 Online:2011-07-20 Published:2011-07-20

RichHTML

2

PDF (PC)

860

Abstract:

Adaptation to low oxygen tension（hypoxia） in cells and tissues induce the transcription of a series of genes that participate in angiogenesis, iron metabolism, glucose metabolism, cell proliferation, and cell survival. Hypoxia inducible factor（HIF）-1 is one of the most important transcriptional activators that mediate these responses. Furthermore, the stability of HIF is regulated by ubiquitination. This article reviews the recent research on the ubiquitination of HIF-1α.

Key words: hypoxia inducible factor-1, ubiquitination, degradation


TrendMD: 
[1] Hao Zhichao1, Meng Yukun2.. Low temperature degradation of dental zirconia ceramic and its influencing factors [J]. Inter J Stomatol, 2012, 39(4): 494-497.
[2] ZOU Duo -hong, HUANG Yuan -liang.. Research progress on hypoxia -inducible factor -1α [J]. Inter J Stomatol, 2010, 37(3): 320-320～323.
[3] HUANG Jia-cheng, LIN Xue-feng. Host-derived matrix metalloproteinase and resin adhesion [J]. Inter J Stomatol, 2010, 37(01): 62-64.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[7] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[8] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[9] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[10] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .