国际口腔医学杂志

国际口腔医学杂志 ›› 2025, Vol. 52 ›› Issue (2): 154-160.doi: 10.7518/gjkq.2025040

• 材料学专栏 • 上一篇    下一篇

新型组织黏合剂在口腔领域的研究进展

韦秀湘(),李昊()   

  1. 广西医科大学口腔医学院/附属口腔医院口腔修复科广西口腔颌面修复与重建研究重点实验室 南宁 530021
  • 收稿日期:2024-07-22 修回日期:2024-12-07 出版日期:2025-03-01 发布日期:2025-03-01
  • 通讯作者: 李昊
  • 作者简介:韦秀湘，住院医师，硕士，Email：wei2022883@163.com
  • 基金资助:
    国家自然科学基金(82060195);广西医疗卫生适宜技术开发与推广应用项目(S2022118)

Research progress of novel tissue adhesives in stomatology

Xiuxiang Wei(),Hao Li()   

  1. Dept. of Prosthodontics, College & Hospital of Stomatology, Guangxi Medical University, Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Nanning 530021, China
  • Received:2024-07-22 Revised:2024-12-07 Online:2025-03-01 Published:2025-03-01
  • Contact: Hao Li
  • Supported by:
    National Natural Science Foundation of China(82060195);Guangxi Medical and Health Appropriate Technology Development and Application Project(S2022118)

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摘要：

组织黏合剂作为止血剂、密封剂、输送载体以及植入式生物医学材料在生物医学工程的不同领域已经得到广泛的研究。近年来，研究者致力于开发适用于潮湿和高动态口腔环境的新型组织黏合剂。与传统组织黏合剂相比，由于具有良好的生物相容性、生物降解性和组织黏附性，新型组织黏合剂在止血、药物输送、组织修复等方面具有很大的优势，在口腔领域显示出广阔的应用前景。本文对口腔领域应用较多的组织黏合剂进行简单分类，重点介绍各种新型组织黏合剂的组成、特性、黏附机制、应用及其存在的问题，旨在为新型组织黏合剂在口腔领域的应用和研究提供参考。

关键词: 组织黏附, 药物递送, 水凝胶, 止血剂, 贻贝, 口腔

Abstract:

Tissue adhesives used as hemostatic agents, sealants, delivery platforms and implantable biomedical mate-rials have been widely studied in different fields of biomedical engineering. In recent years, researchers have focused on developing novel tissue adhesives suitable for moist and highly dynamic oral environments. Compared with traditional tissue adhesives, novel ones have great advantages in hemostasis, drug delivery, tissue repair, and so on, because of their good biocompatibility, biodegradation, and tissue adhesion. As such, these materials show broad application prospects in the oral region. In this paper, tissue adhesives widely used in the field of stomatology are briefly classified, focusing on the composition, characteristics, adhesion mechanism, application, and existing problems of novel adhesives. This work aims to provide reference for the application and research of novel tissue adhesives in this field.

Key words: tissue adhesive, drug delivery, hydrogel, hemostatic agents, mussel, oral

中图分类号: 

  • R318.08
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