Int J Stomatol

Int J Stomatol ›› 2019, Vol. 46 ›› Issue (3): 333-338.doi: 10.7518/gjkq.2019012

• Reviews • Previous Articles     Next Articles

Research progress on the risk factors of median rhomboid glossitis

Yilong Hao,Yu Zhou(),Qianming Chen   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2018-09-26 Revised:2019-01-12 Online:2019-05-01 Published:2019-06-05
  • Contact: Yu Zhou E-mail:812471898@qq.com
  • Supported by:
    This study was supported by National Natural Science Foundation of China(81621002);This study was supported by National Natural Science Foundation of China(81771086);This study was supported by National Natural Science Foundation of China(81470747)

RichHTML

14

PDF (PC)

222

Abstract:

Median rhomboid glossitis (MRG) is a type of tongue disease characterized by shiny oval or diamond-shaped erythematous areas on the dorsal midline of the tongue. The etiological factors of MRG remain unclear. Several possible risk factors cited in the literature include developmental anomalies, candidiasis, smoking, diabetes mellitus, denture wearing, and nutritional factors. Increasing evidence suggests that MRG is strongly associated with chronic candidal infection. Antifungal treatment is usually clinically effective. However, more studies are required to explore how candidiasis causes MRG. The objective of this review is to summarize current research on the risk factors of this tongue disease.

Key words: median rhomboid glossitis, Candida albicans infection, risk factors, therapy

CLC Number: 

  • R781.5

TrendMD: 

Fig 1

A diagram of the diagnosis and treatment of MRG"

[1] Suvarna R, Rao KP, Kini R , et al. Kissing lesion-from tongue to the palate[J]. MOJ Surg, 2018,6(2):17-18.
[2] Mirza D, Raza G, Abassi ZA , et al. Median rhomboid glossitis: a peculiar tongue pathology, report of a case and review of literature[J]. Int J Pharm Biol Sci, 2016,6(4):51-53.
doi: 10.21276/ijpbs
[3] Lago-Méndez L, Blanco-Carrión A, Diniz-Freitas M , et al. Rhomboid glossitis in atypical location: case report and differential diagnosis[J]. Med Oral Patol Oral Cir Bucal, 2005,10(2):123-127.
[4] Bihari M, Srivastava R, Jyoti B , et al. Median rhomboid glossitis with palatal ‘kissing lesion’-A case report[J]. Bangladesh J Dent Res Educ, 2014,4(2):94-97.
doi: 10.3329/bjdre.v4i2.20273
[5] Goregen M, Miloglu O, Buyukkurt MC , et al. Median rhomboid glossitis: a clinical and microbiological study[J]. Eur J Dent, 2011,5(4):367-372.
[6] Ghabanchi J, Andisheh Tadbir A, Darafshi R , et al. The prevalence of median rhomboid glossitis in diabetic patients: a case-control study[J]. Iran Red Crescent Med J, 2011,13(7):503-506.
[7] Rogers RS 3rd, Bruce AJ . The tongue in clinical diagnosis[J]. J Eur Acad Dermatol Venereol, 2004,18(3):254-259.
doi: 10.1111/jdv.2004.18.issue-3
[8] Bojan A, Christy W, Kurian K , et al. A study to determine the association between tobacco smoking habit and oral candidal infection in median rhomboid glossitis by cytologic and histopathologic methods[J]. J Indian Aca Oral Med Radiol, 2012,24(2):106-112.
doi: 10.5005/jp-journals-10011
[9] Reamy BV, Derby R, Bunt CW . Common tongue conditions in primary care[J]. Am Fam Physician, 2010,81(5):627-634.
[10] Cooke BE . Median rhomboid glossitis. Candidiasis and not a developmental anomaly[J]. Br J Dermatol 1975,93(4):399-405.
doi: 10.1111/bjd.1975.93.issue-4
[11] Bae GY, Choi HJ, Chang SE , et al. A case of median rhomboid glossitis[J]. J Dermatol, 2003,30(5):423-425.
doi: 10.1111/jde.2003.30.issue-5
[12] Arendorf TM, Walker DM . The prevalence and intra-oral distribution of Candida albicans in man[J]. Arch Oral Biol, 1980,25(1):1-10.
doi: 10.1016/0003-9969(80)90147-8
[13] Samaranayake LP, Cheung LK, Samaranayake YH . Candidiasis and other fungal diseases of the mouth[J]. Dermatol Ther, 2002,15:251-269.
doi: 10.1046/j.1529-8019.2002.01533.x
[14] Whitaker SB, Singh BB . Cause of median rhomboid glossitis[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 1996,81(4):379-380.
[15] Leite RMS, Leite AAC, Friedman H , et al. Median rhomboid glossitis associated with esophagic candidiasis. A possible etiologic relation with Candida albicans[J]. An bras Dermatol, 2002,77(5):579-583.
doi: 10.1590/S0365-05962002000500008
[16] Farman AG . Atrophic lesions of the tongue: a prevalence study among 175 diabetic patients[J]. J Oral Pathol, 1976,5(5):255-264.
doi: 10.1111/jop.1976.5.issue-5
[17] Farman AG, Nutt G . Oral Candida, debilitating disease and atrophic lesions of the tongue[J]. J Biol Buccale, 1976,4(3):203-226.
[18] Ullmann W, Hoffmann M . Glossitis rhombica mediana. A study of 4 422 dermatologic patients[J]. Hautarzt, 1981,32(11):571-574.
[19] Gümrü B, Kadir T, Uygun-Can B , et al. Distribution and phospholipase activity of Candida species in different denture stomatitis types[J]. Mycopathologia, 2006,162(6):389-394.
doi: 10.1007/s11046-006-0074-1
[20] Galletta VC, Campos MS, Hirota SK , et al. Hyperplastic candidosis on the palate developed as a ‘kissing’ lesion from median rhomboid glossitis[J]. Braz J Otorhinolaryngol, 2010,76(1):137.
doi: 10.1590/S1808-86942010000100023
[21] Borhan Mojabi K, Esfahani M, Bokharaee MM . Evaluation of median rhomboid glossitis and oral lichen planus in patients with diabetes mellitus[J]. JQUMS, 2009,13(1):56-57.
[22] Guggenheimer J, Moore PA, Rossie K , et al. Insulin-dependent diabetes mellitus and oral soft tissue pathologies: Ⅱ. Prevalence and characteristics of Candida and Candidal lesions[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2000,89(5):570-576.
doi: 10.1067/moe.2000.104477
[23] Tapper-Jones LM, Aldred MJ, Walker DM , et al. Candidal infections and populations of Candida albicans in mouths of diabetics[J]. J Clin Pathol, 1981,34(7):706-711.
doi: 10.1136/jcp.34.7.706
[24] Willis AM, Coulter WA, Fulton CR , et al. Oral candida carriage and infection in insulin-treated diabetic patients[J]. Diabet Med, 1999,16(8):675-679.
doi: 10.1046/j.1464-5491.1999.00134.x
[25] Kolokotronis A, Kioses V, Antoniades D , et al. Median rhomboid glossitis. An oral manifestation in patients infected with HIV[J]. Oral Surg Oral Med Oral Pathol, 1994,78(1):36-40.
doi: 10.1016/0030-4220(94)90114-7
[26] Barasch A, Safford MM, Catalanotto FA , et al. Oral soft tissue manifestations in HIV-positive vs. HIV-negative children from an inner city population: a two-year observational study[J]. Pediatr Dent, 2000,22(3):215-220.
[27] Sarode GS, Sarode SC, Patil S . Chronic candidiasis of tongue with kissing lesion on the palate in HIV positive patient[J]. World J Dent, 2014,5(4):247-248.
doi: 10.5005/jp-journals-10015
[28] Rohani B . Oral manifestations and blood profile in patients with iron deficiency anemia[J]. J Formos Med Assoc, 2015,114(1):97.
doi: 10.1016/j.jfma.2014.07.004
[29] Lu SY . Perception of iron deficiency from oral mucosa alterations that show a high prevalence of Candida infection[J]. J Formos Med Assoc, 2016,115(8):619-627.
doi: 10.1016/j.jfma.2016.03.011
[30] Higgs JM, Wells RS . Chronic muco-cutaneous candidiasis: new approaches to treatment[J]. Br J Dermatol, 1973,89(2):179-190.
[31] Bermejo F, García-López S . A guide to diagnosis of iron deficiency and iron deficiency anemia in digestive diseases[J]. World J Gastroenterol, 2009,15(37):4638-4643.
doi: 10.3748/wjg.15.4638
[32] McCullough MJ, Savage NW . Oral candidosis and the therapeutic use of antifungal agents in dentistry[J]. Aust Dent J, 2005,50(4 Suppl 2):S36-S39.
doi: 10.1111/j.1834-7819.2005.tb00383.x
[33] Joseph BK, Savage NW . Tongue pathology[J]. Clin Dermatol, 2000,18(5):613-618.
doi: 10.1016/S0738-081X(00)00137-1
[34] Karen JK, Schaffer JV . Pachyonychia congenita associated with median rhomboid glossitis[J]. Dermatol Online J, 2007,13(1):21.
[35] Rossiello R, Colella G, Satriano RA , et al. Kaposi’s sarcoma of the tongue associated with median rhomboid glossitis in a non-AIDS patient. A case report[J]. Anticancer Res, 2004,24(3b):1897-1900.
[1] Zhang Linlin,Du Yi. Progress on the treatment of palatogingival groove [J]. Int J Stomatol, 2020, 47(4): 458-462.
[2] Min Zhang,Haoyuan Wan. Research progress on drug and laser therapy for peri-implantitis [J]. Int J Stomatol, 2020, 47(4): 463-470.
[3] Tang Bei,Zhao Wenjun,Wang Hu,Zheng Guangning,You Meng. Inferior alveolar nerve injury due to apical overfilling: two cases reports [J]. Int J Stomatol, 2020, 47(3): 293-296.
[4] Yu Lintong,Song Guangtai. Application of erbium laser in pediatric dentistry [J]. Int J Stomatol, 2020, 47(3): 351-355.
[5] Tian Guoli,Jiang Lu,Chen Qianming,Zeng Xin. Research process on parageusia etiology and treatment [J]. Int J Stomatol, 2020, 47(3): 356-361.
[6] Chen Dong,Yang Zheng,Jiang Li. Research progress on the evaluation and management of radiation-induced xerostomia [J]. Int J Stomatol, 2019, 46(6): 711-717.
[7] Wang Liping, Zha Jun, Ge Linhu.. Research progress on non-coding RNAs in tongue squamous cell carcinoma [J]. Inter J Stomatol, 2018, 45(4): 420-424.
[8] Zhang Xiangyi, Liu Yali. Immune regulation of dental stem cells [J]. Inter J Stomatol, 2018, 45(3): 276-279.
[9] Zhu Shanshan, Lu Zhiyue, Wang Shuang. Effects of periodontal basic therapy on pregnancy outcome and inflammatory cytokine of threatened abortion pregnant women [J]. Inter J Stomatol, 2018, 45(3): 319-323.
[10] Ma Yanqun, Li Hong, Hou Benxiang. Research progress on the new attachment of apical periodontal ligament [J]. Inter J Stomatol, 2018, 45(3): 331-334.
[11] Xiao Yandi, Yang Huamei, Dan Hongxia. Adverse reactions of targeted anticancer agents in oral cavity: manifestation and management [J]. Inter J Stomatol, 2018, 45(2): 140-144.
[12] Luo Weidan, Li Mingyun, Zhou Xuedong, Cheng Lei. Application of nano-hydroxyapatite in the clinical treatment of oral diseases [J]. Inter J Stomatol, 2018, 45(2): 192-198.
[13] Yao Yihuan, Wang Jiongke, Zhao Kui, Shi Yujie, Zeng Xin, Chen Qianming. Immunosuppressive adjuvant therapy for pemphigus [J]. Inter J Stomatol, 2018, 45(2): 155-161.
[14] Yao Yihuan, Wang Jiongke, Zeng Xin, Chen Qianming. Adjuvant therapy for pemphigus in addition to glucocorticoid and immunosuppressor [J]. Inter J Stomatol, 2018, 45(2): 162-169.
[15] Xu Xin, He Jinzhi, Zhou Xuedong.. Oral microbiome in the precision medicine [J]. Inter J Stomatol, 2017, 44(6): 619-627.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[7] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 458 -460 .
[8] . [J]. Foreign Med Sci: Stomatol, 2005, 32(06): 452 -454 .
[9] . [J]. Inter J Stomatol, 2008, 35(S1): .
[10] . [J]. Inter J Stomatol, 2008, 35(S1): .