国际口腔医学杂志 ›› 2018, Vol. 45 ›› Issue (2): 214-218.doi: 10.7518/gjkq.2018.02.016
衣晓伟, 黄定明, 张岚
Yi Xiaowei, Huang Dingming, Zhang Lan
摘要: 糖尿病能影响根尖周炎的炎症和骨吸收的发生、发展及预后。国内外学者对于其影响机制做了大量研究。本文就合并糖尿病的牙髓根尖周病的临床表现、糖尿病对牙髓根尖周病的影响机制及糖尿病患者的口腔临床管理进行综述。
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[1] Marotta PS, Fontes TV, Armada L, et al.Type 2 dia-betes mellitus and the prevalence of apical periodon-titis and endodontic treatment in an adult Brazilian population[J]. J Endod, 2012, 38(3):297-300. [2] López-López J, Jané-Salas E, Estrugo-Devesa A, et al.Periapical and endodontic status of type 2 diabetic patients in Catalonia, Spain: a cross-sectional study[J]. J Endod, 2011, 37(5):598-601. [3] Claudino M, Nunes IS, Gennaro G, et al.Diabetes triggers the loss of tooth structure associated to radio-graphical and histological dental changes and its evo-lution to progressive pulp and periapical lesions in rats[J]. Arch Oral Biol, 2015, 60(11):1690-1698. [4] Li DX, Deng TZ, Lv J, et al.Advanced glycation end products (AGEs) and their receptor (RAGE) induce apoptosis of periodontal ligament fibroblasts[J]. Braz J Med Biol Res, 2014, 47(12):1036-1043. [5] Iwama A, Nishigaki N, Nakamura K, et al.The effect of high sugar intake on the development of peri-radicular lesions in rats with type 2 diabetes[J]. J Dent Res, 2003, 82(4):322-325. [6] Ruscitti P, Cipriani P, Di Benedetto P, et al.Mono-cytes from patients with rheumatoid arthritis and type 2 diabetes mellitus display an increased produc-tion of interleukin (IL)-1β via the nucleotide-binding domain and leucine-rich repeat containing family pyrin 3 (NLRP3)-inflammasome activation: a possible im-plication for therapeutic decision in these patients[J]. Clin Exp Immunol, 2015, 182(1):35-44. [7] Cintra LT, Samuel RO, Azuma MM, et al.Apical periodontitis and periodontal disease increase serum IL-17 levels in normoglycemic and diabetic rats[J]. Clin Oral Investig, 2014, 18(9):2123-2128. [8] McAbee J, Li Q, Yu H, et al. Sexual dimorphism in periapical inflammation and bone loss from mitogen-activated protein kinase phosphatase-1 deficient mice[J]. J Endod, 2012, 38(8):1097-1100. [9] Cheng A, Dong Y, Zhu F, et al.AGE-LDL activates Toll like receptor 4 pathway and promotes inflamma-tory cytokines production in renal tubular epithelial cells[J]. Int J Biol Sci, 2013, 9(1):94-107. [10] Chang PC, Chien LY, Chong LY, et al.Glycated matrix up-regulates inflammatory signaling similarly to [11] Kaneko T, Okiji T, Kaneko R, et al.Antigen-presen-ting cells in human radicular granulomas[J]. J Dent Res, 2008, 87(6):553-557. [12] Taşman F, Er N, Ataç A, et al.CD45/isotypes expression in the immune cells of human periapical lesions[J]. J Endod, 2000, 26(3):166-168. [13] Matsui A, Stephens D, Kantarci A, et al.Early cyto-kine response to infection with pathogenic vs non-pathogenic organisms in a mouse model of endodontic infection[J]. PLoS One, 2015, 10(7):e0132752. [14] Duarte PM, Santos VR, Dos Santos FA, et al.Role of smoking and type 2 diabetes in the immunobalance of advanced chronic periodontitis[J]. J Periodontol, 2011, 82(3):429-438. [15] Onal M, Xiong J, Chen X, et al.Receptor activator of nuclear factor κB ligand (RANKL) protein expre-ssion by B lymphocytes contributes to ovariectomy-induced bone loss[J]. J Biol Chem, 2012, 287(35):29851-29860. [16] Plut A, Sprogar Š, Drevenšek G, et al.Bone remode-ling during orthodontic tooth movement in rats with type 2 diabetes[J]. Am J Orthod Dentofacial Orthop, 2015, 148(6):1017-1025. [17] Liu R, Bal HS, Desta T, et al.Diabetes enhances perio-dontal bone loss through enhanced resorption and diminished bone formation[J]. J Dent Res, 2006, 85(6):510-514. [18] Wittrant Y, Gorin Y, Woodruff K, et al.High d(+) glucose concentration inhibits RANKL-induced osteo- clastogenesis[J]. Bone, 2008, 42(6):1122-1130. [19] Li Z, Li C, Zhou Y, et al.Advanced glycation end products biphasically modulate bone resorption in osteoclast-like cells[J]. Am J Physiol Endocrinol Metab, 2016, 310(5):E355-E366. [20] Li J, Liu CY, Jiang YF, et al.Proliferation and diffe-rentiation of human osteoblasts from a type 2 diabetic patient [21] Hou CJ, Liu JL, Li X, et al.Insulin promotes bone formation in augmented maxillary sinus in diabetic rabbits[J]. Int J Oral Maxillofac Surg, 2012, 41(3): 400-407. [22] Schulze A, Schönauer M, Busse M.Sudden improve-ment of insulin sensitivity related to an endodontic treatment[J]. J Periodontol, 2007, 78(12):2380-2384. [23] Michael G.The Oral-systemic gealth connection[M]. Hanover Park: Quintessence Publishing Co, 2014:125-131. [24] Rajeswari K, Kandaswamy D, Karthick S.Endodon-tic management of patients with systemic complica-tions[J]. J Pharm Bioallied Sci, 2016, 8(Suppl 1):S32-S35. [25] Weng J, Ji L, Jia W, et al.Standards of care for type 2 diabetes in China[J]. Diabetes Metab Res Rev, 2016, 32(5):442-458. [26] McKenna SJ. Dental management of patients with diabetes[J]. Dent Clin North Am, 2006, 50(4):591-606. [27] Clark BM, Homeyer DC, Glass KR, et al.Clindamycin-induced Sweet’s syndrome[J]. Pharmacotherapy, 2007, 27(9):1343-1346. [28] Haji IU, Siddiq M, Rao S, et al.Study on blood glu-cose concentration in patients with diabetes under-going dental extraction under local anesthesia with and without adrenaline[J]. J Basic Clin Physiol Phar-macol, 2012, 23(4):169-171. [29] Santos-Paul MA, Neves IL, Neves RS, et al.Local anesthesia with epinephrine is safe and effective for oral surgery in patients with type 2 diabetes mellitus and coronary disease: a prospective randomized study[J]. Clinics, 2015, 70(3):185-189. |
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