儿童复发性阿弗他溃疡病因学的研究进展

doi:10.7518/gjkq.2018.02.005

国际口腔医学杂志 ›› 2018, Vol. 45 ›› Issue (2): 145-149.doi: 10.7518/gjkq.2018.02.005

儿童复发性阿弗他溃疡病因学的研究进展

蔡东霖¹, 卢锐^1,2

1.口腔基础医学省部共建国家重点实验室培育基地和口腔生物医学教育部重点实验室,武汉大学口腔医学院武汉 430079
2.武汉大学口腔医院口腔黏膜科武汉 430079

收稿日期:2017-09-21 修回日期:2017-11-02 出版日期:2018-03-01 发布日期:2018-03-01
通讯作者: 卢锐,副主任医师,博士,Email：lurui@whu.edu.cn
作者简介:蔡东霖,硕士,Email：2012302220028@whu.edu.cn
基金资助:
武汉中青年医学骨干人才培养工程（2017年第五批）

Research progress on the etiology of recurrent aphthous ulcer in children

Cai Donglin¹, Lu Rui^1,2

1.The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) &Key Laboratory of Oral Biomedicine Ministry of Education, School of Stomatology, Wuhan University, Wuhan 430079, China;
2.Dept. of Oral Medicine, Hospital of Stomatology, Wuhan University, Wuhan 430079, China

Received:2017-09-21 Revised:2017-11-02 Online:2018-03-01 Published:2018-03-01
Supported by:
This study was supported by the Cultivation Project of Wuhan Young and Middle-aged Backbone Talent in Medicine (the fifth batch of 2017).

摘要/Abstract

摘要： 复发性阿弗他溃疡（RAU）是最常见的口腔黏膜溃疡类疾病,虽然在各个年龄段均可发病,但其首发多见于儿童期。RAU儿童作为该病患者中的特殊群体,在病因学上具有一定的特殊性。目前已知的与儿童RAU有关的病因包括遗传因素、局部创伤、心理因素、营养缺乏、微生物感染、免疫反应异常等,此外,一些儿童RAU还与多种全身系统疾病有关,本文针对儿童RAU病因学的研究进展作一综述。

关键词: 复发性阿弗他溃疡, 儿童, 病因

Abstract: Recurrent aphthous ulcer (RAU) is the most common ulcerative disease of the oral mucosa. Although RAU appears in all ages, the onset of RAU peaks during childhood. Childhood RAU, as a special patient group, displays distinct etiology. The etiology of childhood RAU includes genetic, local trauma, psychologic, nutritional factors, microbial infection, and abnormal immunologic response. Moreover, some cases of childhood RAU are associated with several systemic diseases. This article presents the current progress on the etiology of RAU in children.

Key words: recurrent aphthous ulcer, children, etiology

中图分类号:

R781.5

蔡东霖, 卢锐. 儿童复发性阿弗他溃疡病因学的研究进展[J]. 国际口腔医学杂志, 2018, 45(2): 145-149.

Cai Donglin, Lu Rui. Research progress on the etiology of recurrent aphthous ulcer in children[J]. Inter J Stomatol, 2018, 45(2): 145-149.

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儿童复发性阿弗他溃疡病因学的研究进展

Research progress on the etiology of recurrent aphthous ulcer in children

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