Table of Content

    01 November 2016, Volume 43 Issue 6 Previous Issue    Next Issue
    Common dental diseases in children and malocclusion
    Zou Jing1, Qin Man2, Wang Jun3, Huang Hua4, Lin Juhong5, Zhou Xuedong1.
    Inter J Stomatol. 2016, 43 (6):  619-623.  DOI: 10.7518/gjkq.2016.06.001
    Abstract ( 1382 )   HTML ( 36 )   PDF(pc) (3492KB) ( 1331 )   Save

    Caries and its complications, dental trauma, occlusive disorders, dental dysplasia is common in pediatric dental clinic treatment. The clinical work in pediatric dentistry requires not only a variety of common dental treatment for children, but also need to manage their oral health, from the first tooth eruption, successfully establishing a healthy primary dentition, mixed dentition, until the establishment of the normal young permanent dentition. Malocclusion in children occur not only related to genetic factors, deciduous caries, endodontic disease, dental trauma, improper feeding practice and poor diet can cause occlusive disorders and malocclusion. In this paper, starting from childhood caries, talk about some relations of several common dental diseases with the malocclusion of children, in order to provide evidences to pediatric dentists and general dentists with a view of systematic management of children’s oral health.

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    Oral hygiene after oral and maxillofacial surgery
    Liu Dongling1, Li Xiue2, Zhao Forong3
    Inter J Stomatol. 2016, 43 (6):  624-631.  DOI: 10.7518/gjkq.2016.06.002
    Abstract ( 1154 )   HTML ( 18 )   PDF(pc) (1167KB) ( 1114 )   Save
    Oral maxillofacial surgery patients to keep clean, related to the postoperative patients of comfort, loss of appetite, whether oral complications, postoperative wound healing and rehabilitation is the most focus on oral cavity nursing professionals, one of the most with specialized characteristics of nursing measures, therefore, how to effectively postoperative patients with oral cavity clean and maintenance, to achieve a better oral cleaning effect, anyone is often heard.The current schools of thought contend column invited three oral care experts, on the issue in the concrete work of clinical response are discussed.
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    Comparison of geriatric oral health assessment index and oral health impact profile-14 as measures of oral healthrelated quality of life of middle-aged and elderly individuals in southwest China
    Deng Yuejia1, Wang Chenbing1, Zhang Ximu1, Yue Zhaoguo1, Liu Yunkun1, Jin Zhenning1, Zhao Man2.
    Inter J Stomatol. 2016, 43 (6):  632-635.  DOI: 10.7518/gjkq.2016.06.003
    Abstract ( 970 )   HTML ( 11 )   PDF(pc) (1154KB) ( 528 )   Save
    Objective This study compares oral health-related quality of life among middle-aged and elderly individuals in southwest China by geriatric oral health assessment index(GOHAI) and oral health impact profile-14(OHIP-14) scales, to test the reliability of GOHAI and OHIP-14 scales, and to select the more effective scale in evaluating oral health-related quality of life of rural middle-aged and elderly individuals. Methods Surveys with OHIP-14 and GOHAI scales were conducted face-to-face among rural middle-aged and elderly individuals above 45 years old from Qingchuan Sichuan and Xishui Guizhou randomly. Differences between the two scales were compared by Paired sample t-test(P=0.05). Reliability was evaluated by Cronbach’s alpha. Results GOHAI and OHIP-14 scales were highly consistent in assessing oral health-related quality of life in the same subject. GOHAI and OHIP-14 scores of middle-aged and elderly people showed differences in each dimension except for the psychological dimension. Reliability analysis showed that OHIP-14 is inherently more stable and reliable. Conlusion OHIP-14 scale is more suitable for the evaluation of oral health quality of life among middle-aged and elderly individuals in rural southwest China.
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    Roles of erythropoietin on the differentiation of osteoblasts
    Zhang Jiaxi1, He Meili1, Zhao Bingsong1, Li Linmei2
    Inter J Stomatol. 2016, 43 (6):  636-639.  DOI: 10.7518/gjkq.2016.06.004
    Abstract ( 924 )   HTML ( 9 )   PDF(pc) (2403KB) ( 570 )   Save
    Objective This study aimed to investigate the effects of erythropoietin(EPO) on the differentiation and function of osteoblasts, to identify the roles of EPO-erythropoietin receptor(EPOR) in osteoblasts, and to explore the effects and mechanism of EPO in bone homeostasis. Methods Mouse bone marrow stromal cell line ST2 was cultured in vitro and treated with EPO. Changes in osteoblastic gene levels were quantified by real-time polymerase chain reaction. The function of osteoblasts in bone formation was observed by alkaline phosphatase(ALP) and alizarin red staining. EPOR expression was knocked down by RNA interfere. The differentiation and function of osteoblasts were then tested by the above methods. Results ST2 cells expressed EPOR. After binding with EPOR, EPO induced osteoblast differentiation from bone marrow stromal cells. Expression levels of osteoblast-related genes Runx2, Alp, and Col1 increased. ALP and calcium deposition increased. Expression levels of osteoblast-related genes were repressed after EPOR knockdown. Conclusion EPO promotes the differentiation and function of osteoblasts through EPO-EPOR signaling.
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    Individual treatment of velopharygeal incomplete after palatoplasty
    Li Sheng, Jiang Hongbing, Wan Linzhong, Yuan Hua, Wang Binbing, Jiang Chenghui, Du Yifei.
    Inter J Stomatol. 2016, 43 (6):  640-644.  DOI: 10.7518/gjkq.2016.06.005
    Abstract ( 1135 )   HTML ( 8 )   PDF(pc) (3263KB) ( 511 )   Save
    Objective This study investigates the individual treatment of velopharyngeal incomplete(VPI) after palatoplasty. Methods Forty-eight patients with VPI were recruited. Physical examinations, including nasopharyngeal fiberscope examination, were performed on the basis of medical history. Patients were divided into three groups according to examination results. Group A comprised patients with velopharyngeal closure rate above 80% and slight distance between the posterior edge of the soft palate to the posterior wall. Group B comprised patients with velopharyngeal closure rate of less than 80%, shortened soft palate, and unobservable movement of the lateral pharyngeal wall. Group C comprised patients with velopharyngeal closure rate of less than 80%, shortened soft palate, and good movement of the lateral pharyngeal wall. Treatments for the three groups were designed differently. Results The speech results of all 48 patients significantly improved after individual surgical treatment. Conclusion Individual treatment plan should be designed on the basis of detailed examination in patients with VPI after palatoplasty.
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    Clinical significance of serum squamous cell carcinoma antigens in Uyghur patients with oral squamous cell carcinoma
    Liu Pan1, Duolikun?Wufuer1, Cai Zhigang2, Sun Jian3
    Inter J Stomatol. 2016, 43 (6):  645-650.  DOI: 10.7518/gjkq.2016.06.006
    Abstract ( 714 )   HTML ( 5 )   PDF(pc) (1082KB) ( 404 )   Save
    Objective This study investigates the expression of squamous cell carcinoma antigen(SCC-Ag) levels in patients with Uyghur oral squamous cell carcinoma(OSCC). Methods Serum SCC-Ag levels were measured in 90 Uyghur patients with OSCC(OSCC group), 90 Uyghur patients with other oral malignant tumors(oral malignant tumor except OSCC group), 101 Uyghur patients with oral benign tumors(benign tumor group), and 120 healthy Uyghur people(healthy group). SCC-Ag levels were measured in 60 OSCC cases and 60 cases of oral malignant tumor except OSCC before and after treatment. The significance of SCC-Ag in the diagnosis and treatment of OSCC was analyzed. Results SCC-Ag levels in OSCC group were significantly higher than in oral malignant tumor except OSCC group(P=0.002), benign tumor group(P=0.001), and healthy group(P=0.001). Serum SCC-Ag positive rate in OSCC group was 43.3% (39/90) and was significantly higher compared with the other three groups(P=0.000 1). SCC-Ag expression was higher in preoperative OSCC group in late TNM stage compared with patients in early TNM stage(P<0.05). Preoperative and postoperative patients who received radiation and chemotherapy treatment were further classified into the recurrence group and non-recurrence group, the difference in SCC-Ag levels between groups was statistically significant(P<0.05). The difference between SCC-Ag levels in groups with squamous carcinoma before and after surgical, radiation, and chemotherapy treatment was statistically significant(P<0.01). However, the curative effect of SCC-Ag levels in oral malignant tumor except OSCC group was not statistically significant(P>0.05). Conclusion Serum SCC-Ag levels were not highly sensitive in Uyghur patients with early-stage OSCC. However, SCC-Ag has clinical significance in the evaluation of curative effect as a predictor of tumor recurrence.
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    Association between objective and subjective evaluations on masticatory efficiency and quality of life in patients with prostheses
    Zhang Rubin, Zeng Xiaojuan, Li Yajuan, Lin Weiyuan.
    Inter J Stomatol. 2016, 43 (6):  651-653.  DOI: 10.7518/gjkq.2016.06.007
    Abstract ( 654 )   HTML ( 5 )   PDF(pc) (1058KB) ( 627 )   Save
    Objective This study explores the association between objective and subjective evaluations of differenttypes of prostheses and to establish a simple and effective method to evaluate masticatory efficiency and quality of life in patients with prostheses. Methods The sample consisted of 93 patients who received removable partial dentures and fixed dentures during July 2012 to July 2013 from Hospital of Stamotology, Guangxi Medical University. Clinical data were collected by oral examination and subjective data were obtained by face-to-face interviews with index of eating difficulty(IED) and oral impact daily performance(OIDP). Masticatory efficiency test was conducted at the laboratory. All data were collected before and 3 months after restoration surgery. Data were analyzed with SPSS 16.0. Results Masticatory efficiency increased after restoration surgery. IED and OIDP scores decreased after restoration surgery. There were significant negative relationships between masticatory efficiency and IED and OIDP scores before and after restoration surgery. Masticatory efficiency increased whereas IED and OIDP scores decreased. Conclusion IED and OIDP are simple and effective methods to evaluate quality of life and masticatory efficiency in patients with prostheses.
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    Investigation of payment and benefits for orthodontic treatment
    Pu Panjun, Lu Ying, Ge Tiange, Zhang Sha, Chen Zewen, Huang Ning.
    Inter J Stomatol. 2016, 43 (6):  654-657.  DOI: 10.7518/gjkq.2016.06.008
    Abstract ( 706 )   HTML ( 8 )   PDF(pc) (1420KB) ( 495 )   Save
    Objective This study investigates the cost and benefits of orthodontic treatment. Methods We recruited 150 orthodontics patients. The sample group comprised 30 patients under 12 years old, 60 patients aged 12 to 18 years old, and 60 patients aged 18 years old or above. We issued 150 copies of valid questionnaires to the subjects. Statistical analysis was performed by SPSS statistical software. Results Differences were statistically significant among aspects of orthodontic cost, subjective feelings during treatment, duration of treatment, subjective feelings about duration of treatment, self-evaluation after treatment, and post-treatment effects on nutrition, mental state, and chewing. No differences were statistically significant among aspects of treatment time and the effects on pronunciation after treatment. Conclusion Differences in payment and benefits were found among different age groups.
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    Three-year clinical evaluation of all ceramic crowns bonded with self-etch and self-adhesive resin cements
    Wu Fangyan, Li Mingfei, Meng Xiangfeng.
    Inter J Stomatol. 2016, 43 (6):  658-660.  DOI: 10.7518/gjkq.2016.06.009
    Abstract ( 995 )   HTML ( 13 )   PDF(pc) (1027KB) ( 750 )   Save
    Objective To observe and evaluate 3-year clinical effect of all ceramic crowns bonded with 2 types of resin cement. Methods 218 all ceramic crowns (E.MAX) from 154 patients were selected. A self-etch resin cement-PANAVIA F and a self-adhesive resin cement-Rely X Unicem were used to bond all ceramic crown with abutment, and the surfaces of abutments were pretreated by ED-Primer before using PANAVIA F. The inner surfaces of all ceramic crowns were pretreated by silane coupling agent before cementation. Survive rates of 3-year follow-up were calculated according to the fracture/debond number of crowns bonded with each resin cement. Results Survive rates of crowns bonded with PANAVIA F and Rely X Unicem were irrespectively 97.5%, and 96.0%. And debonded cases were the posterior abutments with large composite resin restoration. Conclusion The bond of E.MAX all ceramic crowns by either PANAVIA F or Rely X Unicem demonstrated satisfactory 3-year clinical performance.
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    Immunohistochemical localization and antimicrobial properties of high mobility group protein N2
    Liu Yi1, Zhou Rongjing2, Fei Wei1.
    Inter J Stomatol. 2016, 43 (6):  661-665.  DOI: 10.7518/gjkq.2016.06.010
    Abstract ( 651 )   HTML ( 5 )   PDF(pc) (4599KB) ( 455 )   Save
    Objective To study immunohistochemical localization of high mobility group protein N2(HMGN2) protein in porcine tissues, and evaluate the antimicrobial activity of its active domain, α-helical domain in vitro. Methods In this study, we investigated the localization of HMGN2 protein in porcine tissues using the immunohistochemical method. In addition, we isolated and purified HMGN2 from porcine thymus and lymph node by the high-performance liquid chromatography(HPLC), and then we synthesized α-helical domain of HMGN2. After that, we evaluated the antimicrobial activity of HMGN2 and α-helical domain of HMGN2, against Streptococcus mutans, Streptococcus sobrinus, Candida albicans and Escherichia coli in vitro. Results The results showed that HMGN2 could be isolated and purified from porcine thymus and lymph node, and all the tested porcine tissues were immunoreactive to HMGN2 proteins. The proteins mostly presented in the cytoplasm and nucleus. Synthetic α-helical domain of HMGN2 and HMGN2 had equivalent antibacterial activity, and both of them had potent antimicrobial activity against the selected bacteria and fungi. Conclusion The study suggested that the HMGN2 proteins mostly presented in the cytoplasm and nucleus in porcine tissues, and HMGN2 and synthetic α-helical domain of HMGN2 had potent antimicrobial activity against some bacteria and fungi.
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    A case report about maxillary birooted primary canines
    Liu Yonghong1, Liu Zhenli1, Hao Yan2.
    Inter J Stomatol. 2016, 43 (6):  666-667.  DOI: 10.7518/gjkq.2016.06.011
    Abstract ( 862 )   HTML ( 12 )   PDF(pc) (1772KB) ( 537 )   Save
    Birooted primary canines is a heteroplasia of teeth that is very rare in clinical practice. The prevalence of birooted primary canines appears to be higher in the maxilla than the mandibula, and birooted primary canines often seem to occur bilaterally. In this article, a case of birooted primary canines with bilateral maxilla is reported, and relevant literature is reviewed.
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    Review on the determinants of dental service utilization
    Chen Litong, Wang Yong, Lü Peijun.
    Inter J Stomatol. 2016, 43 (6):  668-671.  DOI: 10.7518/gjkq.2016.06.012
    Abstract ( 643 )   HTML ( 8 )   PDF(pc) (1058KB) ( 482 )   Save
    The determinants of oral service utilization mainly include four aspects: socioeconomic factors, dental and overall health status, dental health-related perception, and dental health-related behavior. This review summarizes these aspects to provide a basis for dental health improvement and dental service promotion.
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    Research progress on piezosurgery in the application of endodontic surgery
    Chen Yao1, Shen Jing2.
    Inter J Stomatol. 2016, 43 (6):  672-676.  DOI: 10.7518/gjkq.2016.06.013
    Abstract ( 881 )   HTML ( 16 )   PDF(pc) (1044KB) ( 708 )   Save
    The piezosurgery device is a new developed surgical equipment, which used piezoelectric ultrasonic vibrations to cut bone atraumatically and to provide an alternative to the mechanical and electrical instruments used in conventional oral surgery. It has been widely used in oral sugery, such as maxillofacial surgery, maxillary sinus lifting and periodontal surgery, et al. Recently, piezoelectric instruments can be applied in endodontic surgery, reducing the risk of damage to soft tissue, providing a clear operative filed, and cutting without generating heat. This review summarizes the operating principles of piezosurgery device and outlines the applications of pizeosurgery in endodontic surgery.
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    Research progress on mammary analogue secretory carcinoma of salivary gland
    Sun Jingjing, Li Jiang.
    Inter J Stomatol. 2016, 43 (6):  677-684.  DOI: 10.7518/gjkq.2016.06.014
    Abstract ( 1319 )   HTML ( 13 )   PDF(pc) (1156KB) ( 540 )   Save
    Mammary analogue secretory carcinoma(MASC) is a salivary gland tumor that harbors the specific E-twenty six variant gene 6-nerve nutrition tyrosine receptor kinase 3 translocation which resembles secretory carcinoma of the breast. MASC exhibits morphological features similar to other salivary gland tumors and is thus often pathologically diagnosed as acinic cell carcinoma and mucoepidermoid carcinoma. This paper reviews the clinical manifestations, pathological features, molecular characteristics, differential diagnosis, prognosis, and treatment of MASC.
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    Biological functions of microRNA-203 and its role in oral diseases
    Geng Fengxue, Pan Yaping.
    Inter J Stomatol. 2016, 43 (6):  685-689.  DOI: 10.7518/gjkq.2016.06.015
    Abstract ( 609 )   HTML ( 14 )   PDF(pc) (1118KB) ( 434 )   Save
    MicroRNA-203(miR-203) plays important roles in the development and progression of tumor and inflammation by targeting and regulating various downstream mediators at different levels. MiR-203 is a novel diagnostic and prognostic marker because of its therapeutic potential. The intensive investigation of mechanism in tumor development within micro-environment of inflammation has made the potent role of miR-203 in regulating inflammation-related tumor a new controversial issue. Recently, the regulatory mechanisms of miR-203 have been investigated in oral diseases. This mini-review focuses on the biological function of miR-203, especially its role in oral diseases.
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    Clinical research progress on all-ceramic resin-bonded fixed partial dentures
    Chen Junyu, Wan Qianbing.
    Inter J Stomatol. 2016, 43 (6):  690-694.  DOI: 10.7518/gjkq.2016.06.016
    Abstract ( 1048 )   HTML ( 10 )   PDF(pc) (1044KB) ( 810 )   Save
    According to the concept of minimally invasive dentistry, resin-bonded partial dentures have been widely used for replacement of a missing tooth. The development of all-ceramic materials and adhesive techniques has facilitated the use of all-ceramic resin-bonded fixed partial dentures for partial edentulism. Such type of dentures has advantages of minimal invasiveness and aesthetics. All-ceramic resin-bonded fixed partial dentures possess a high short-term success rate when used in an appropriate way. However, the long-term clinical success rates remain uncertain. This article reviewed the clinical research progress on abutment selection, design, adhesive technique, and prognosis of all-ceramic resin-bonded fixed partial dentures.
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    Research progress on the effect of micro-arc oxidation on the bonding strength between pure titanium and porcelain
    Yuan Xiaohui, Liu Jie.
    Inter J Stomatol. 2016, 43 (6):  695-699.  DOI: 10.7518/gjkq.2016.06.017
    Abstract ( 548 )   HTML ( 8 )   PDF(pc) (1111KB) ( 516 )   Save
    Micro-arc oxidation(MAO) forms an oxide layer with porous surface and inner compact structure on the pure titanium surface. This oxide layer could significantly affect titanium-porcelain bonding strength. Technological parameters, such as pulse frequency, duty cycle, and voltage, as well as electrolyte, strongly affect the structure and property of ceramic coatings formed through micro-arc oxidation. This review presents the research advancement of micro-arc oxidation in improving the bonding between pure titanium and porcelain.
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    Effects of biological stress and mitogen-activated protein kinase on bone remodeling
    Geng Yuanming1, Shen Xiaoqing1, Xu Pingping2.
    Inter J Stomatol. 2016, 43 (6):  700-705.  DOI: 10.7518/gjkq.2016.06.018
    Abstract ( 706 )   HTML ( 6 )   PDF(pc) (1127KB) ( 359 )   Save
    Studies on mechanotransduction have focused on stomology-related bone biology. In in mechanotransduction, cellular responses to mechanical stress, such as fluid shear stress or matrix deformation in vitro, involve multiple signal pathways, including mitogen-activated protein kinase pathway. This pathway is activated through integrin, calcium channel, and lipid raft under mechanical stress and regulates downstream signal molecules, such as transcription factor core binding factors α1 and activator protein-1. Crosstalks are present between mechanical stress-induced mitogen-activated protein kinase pathway and other receptor pathways(such as estrogen, parathyroid hormone, and 1,25-dihydroxy-cholecalciferol receptor pathways). These crosstalks are important regulatory mechanisms of mechanotransduction.
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    Relationship between prediabetes and periodontitis
    Huang Yanli, Guo Weihua, Tian Weidong.
    Inter J Stomatol. 2016, 43 (6):  706-710.  DOI: 10.7518/gjkq.2016.06.019
    Abstract ( 925 )   HTML ( 11 )   PDF(pc) (1114KB) ( 828 )   Save
    Prediabetes is a metabolic abnormality, and periodontitis is a chronic infection caused by bacteria and is characterized by the destruction of periodontal tissues. Clinical and epidemiological studies show that prediabetes and periodontitis are related. Prediabetes may increase the prevalence rate and severity of periodontitis, and periodontitis could aggravate the severity of prediabetes. Moreover, periodontal therapy could improve the glucose homeostasis of prediabetes. Both diseases may involve oxidative stress and inflammatory cytokines, including tumor necrosis factor-α, interleukin(IL)-1β, and IL-6. Obesity and age are common risk factors that promote the onset and development of the two diseases. In this paper, the correlation and interaction mechanism between prediabetes and periodontitis are reviewed.
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    Research progress on the synergy between herpes viruses and periodontopathic bacteria
    Deng Fengying, Lin Zhiyong.
    Inter J Stomatol. 2016, 43 (6):  711-716.  DOI: 10.7518/gjkq.2016.06.020
    Abstract ( 705 )   HTML ( 8 )   PDF(pc) (1123KB) ( 544 )   Save
    Viral infection of periodontal herpes is typically associated with the increased occurrence of periodontopathic bacteria, and herpes virus display a strong synergy effect with periodontal pathogens through various mechanisms. Prevalence of herpes virus in the subgingival dental plaque of periondontitis patients was higher than that of periodontal healthy controls. Pathogenic synergy existed throughout the process of periodontitis by different mechanisms, including adhesion and colonization of periodontal pathogenic bacteria, reactive of herpes virus, and impairment of host antibacterial immune. These mechanisms can better explain the clinical characteristics of periodontitis. When the biological link in periomedicine concept is established through virus-induced molecular pathway of herpes, the conventional periodontal therapy directed at bacteria may be inefficient in periodontitis treatment while the treatment employing antiviral agents may be significantly effective. The concept of herpesviral-bacterial coinfection in periodontitis is an interesting topic for future research. This paper reviews the research progress in the study of interactions between herpes virus and periodontopathic bacteria in periodontal diseases.
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    Influencing factors of the prognosis of apical microsurgery
    Gao Jing, Shen Jing.
    Inter J Stomatol. 2016, 43 (6):  717-720.  DOI: 10.7518/gjkq.2016.06.021
    Abstract ( 626 )   HTML ( 11 )   PDF(pc) (1037KB) ( 526 )   Save
    The high success rate of apical surgery is attributed to the extensive use of oral microscope and ultrasonicinverted preparation equipment, as well as the good biocompatibility of the technique. Factors influencing the prognosis of microsurgical operation of the root tip must be elucidated to provide a reference for selecting clinical cases and developing accurate and effective treatment plans. In this paper, factors affecting the prognosis of patients who underwent apical microsurgery are reviewed based on three aspects: patient, teeth, and operation.
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    Research progress on prognosis factors of endodontic surgery
    Li Ruhuang, Wang Xiao.
    Inter J Stomatol. 2016, 43 (6):  721-724.  DOI: 10.7518/gjkq.2016.06.022
    Abstract ( 1076 )   HTML ( 17 )   PDF(pc) (1037KB) ( 615 )   Save
    Endodontic surgery is a valuable option for maintaining patient’s natural dentition when previous orthograde endodontic treatments fail to succeed. Generaly, the surgical success rate can be up to 90%. Several factors are associated with the outcome of the surgery. Theoretically, the general health or systemic illness which affect the healing up of the wound are related to the surgery prognosis, such as diabetes, anemia, radiation treatment etc. Besides, the tooth position, the bone defect situation, whether the bone defect is through with the periodontal pocket, preoperative root canal treatment etc, are also associated with the surgical outcome. Before the surgery, serious examination, proper surgical devices and materials should be prepared, because it intensely affects the surgical success rate. Aesthetic factors should also be taken in account during the operation. To obtain better aesthetic results, design of the approach mucosal flap is the key point. Of all the factors involving the prognosis of endodontic surgery, retro-filling materials and magnified devices is considered the major factors in some articles. The factors related with endodontic surgery are various, but how they act with each other is still unknown. To answer this question, further research is necessary.
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    Application of computer aided surgery system and 3D printing technology in the reconstruction of the defects in oral and maxillofacial region
    Wang Jing, Yuan Rongtao, Dong Qian.
    Inter J Stomatol. 2016, 43 (6):  725-728.  DOI: 10.7518/gjkq.2016.06.023
    Abstract ( 594 )   HTML ( 12 )   PDF(pc) (1083KB) ( 634 )   Save
    The rapid development of digital medicine brought the revolutionary change to clinical medicine, which was an emerging interdisciplinary field. The development and application of computer aided surgery system made the medicine enter a completely new visual information age especially, which promoted the development of precise and effective surgical treatment for qualitative leap and triggers a technology revolution in the field of surgery with the combination of 3D printing technology. The computer aided surgery system with 3D printing technology was extensively and profoundly applied in reconstruction of the defect in oral and maxillofacial region, which was complex and demanding. The paper reviewed the application and progress of computer aided surgery system and 3D printing technology in reconstruction of the defect in oral and maxillofacial region.
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    Application of collagen and growth factors for bone and nerve healing processes
    Zhu Chenyou, Cao Yubin, Deng Jia, Qi Wenting, Cao Cong, Shi Bing.
    Inter J Stomatol. 2016, 43 (6):  729-733.  DOI: 10.7518/gjkq.2016.06.024
    Abstract ( 1380 )   HTML ( 9 )   PDF(pc) (1116KB) ( 860 )   Save
    Collagen possesses weak antigenic activity, high biocompatibility, biodegradability, and biomechanical properties. It has been widely used in tissue engineering of various organs, such as skin, tendons, blood vessels, nerves, and bones. Growth factors are a class of molecules that effectively regulate cell metabolism and tissue repair. Collagengrowth factor biomaterials(CGFB) exhibit desirable biological and biomechanical properties in osteogenesis, nerve repair, tendon reconstruction, and repair of chronic wounds. In the process of osteogenesis, CGFB ideally release growth factors, effectively inducing osteogenic differentiation of stem cells, thus promoting repair in bone defects. In the process of nerve repair, a specific design of CGFB for a purpose can effectively promote neuritis generation. In the process of central nervous system repair, the injection of collagen gel can provide a desirable microenvironment for cells, which is beneficial for central nervous system repair. This article reviews the basic properties and recent studies in bone and nerve repair of CGFB to provide future direction of improvement.
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    Role of microRNA-205 on chemoresistance and its mechanism in tumor
    Li Long, Huang Hongzhang.
    Inter J Stomatol. 2016, 43 (6):  734-738.  DOI: 10.7518/gjkq.2016.06.025
    Abstract ( 687 )   HTML ( 9 )   PDF(pc) (1048KB) ( 742 )   Save
    Resistance to chemotherapeutic drugs is a difficult problem that often leads to the failure of chemotherapy in tumor clinical treatment. Chemoresistance mechanism involves the complex and unclear regulation of multiple genes and signaling pathways. MicroRNA(miRNA) are endogenous, small non-coding, single-strand RNA molecules that are 18-25 nucleotides in length. They play a crucial role in regulating various cellular biological processes. Accumulated studies show that aberrant expression of miRNA is associated with progression, migration, and chemotherapy resistance in various cancers. Recently, an increasing number of studies reveal that miRNA-250(miR-205) participates in regulating chemotherapy resistance in cancers. However, the role of miR-205 in chemoresistance is still unclear. This paper reviews the relationship between miR-205 and chemotherapy resistance in tumors.
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    Nurse-patient communication skills in orthodontics
    Zhang Anxiang, Liu Manli, Zheng Yingcheng, Xu Fangqing.
    Inter J Stomatol. 2016, 43 (6):  739-742.  DOI: 10.7518/gjkq.2016.06.026
    Abstract ( 2174 )   HTML ( 39 )   PDF(pc) (1060KB) ( 804 )   Save
    Increasing aesthetic demands have caused many individuals to seek orthodontic treatment. Such treatment is challenged by differences in nurse personal qualities, specialized knowledge, and communication ability, as well as the growing number of patients with varied age-sex compositions, obvious psychological factors, individualized demands. The rapid development in clinical techniques and materials is also difficult to cope with. Fortunately, the easy access to multimedia and the development of network technique promote facilitated nurse-patient communication. In this review, we summarize the characteristics and influencing factors of the nurse-patient communication in orthodontic treatment and then discuss various communication skills and their clinical application to improve the efficiency of clinical treatment and patient satisfaction.
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