Int J Stomatol

Inter J Stomatol ›› 2008, Vol. 35 ›› Issue (2): 131-134.

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The effects of enamel matr ix proteins on the signal tr ansduction pathway

YU Guang, SHU Rong   

  1. Dept. of Periodontology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200011, China
  • Received:2007-06-09 Revised:2007-08-20 Online:2008-03-20 Published:2008-03-20
  • Contact: SHU Rong

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Abstract:

Local application of biologic regulator in operating area to promote regeneration has become a burning topic in the periodontological domain. Enamel matrix proteins have been demonstrated satisfactory effect in the periodontal
regeneration studies. However, the precise mechanism of the biological function is still indefinite. Various responds such as proliferation and differentiation induced by stimulus is regulated by the expression and/or activation of response factors, which constitute the signal transduction pathway.

Key words: enamel matrix proteins, signal transduction, endothelial cell, fibroblast


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