Int J Stomatol ›› 2021, Vol. 48 ›› Issue (3): 318-321.doi: 10.7518/gjkq.2021052

• Case Report • Previous Articles     Next Articles

Treatment of verrucous leukoplakia recurred after surgical excision using photodynamic therapy: a case report

Li Zheru(),Dan Hongxia,Chen Qianming()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & National Key Laboratory of Oral Mucosal Diseases & Innovation Unit of Oral Mucosal Carcinogenesis and Prevention, Chinese Academy of Medical Sciences & Dept. of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2020-11-05 Revised:2021-01-21 Online:2021-05-01 Published:2021-05-14
  • Contact: Qianming Chen;
  • Supported by:
    National Nature Science Foundation of China(82071125);Joint Fund from the National Nature Science Foundation of China(U19A2005);Sichuan Science and Technology Program(2020YFS0044);Sichuan Science and Technology Program(2020YFSY009);Research and Develop Program of West China Hospital of Stomatology, Sichuan University(LCYJ2019-11)


Oral leukoplakia (OLK) is a common type of potentially malignant disorder with certain risk of malignant transformation. Nonhomogeneous type such as verrucous type has higher rate of malignant transformation than homogeneous type. Traditional treatment cannot remove the lesion while retain the appearance and normal function of the treated area, and recurrence is very common. Photodynamic therapy is a minimally invasive treatment modality and has great potential in the treatment of OLK. In this manuscript, a case of verrucous OLK which recurred after surgical movement was treated with photodynamic therapy.

Key words: oral leukoplakia, verrucous leukoplakia, photodynamic therapy

CLC Number: 

  • R781.05


Fig 1

Figures of clinical lesions before operation"

Fig 2

Treatment process and effect"

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