Int J Stomatol

Inter J Stomatol ›› 2014, Vol. 41 ›› Issue (4): 383-386.doi: 10.7518/gjkq.2014.04.003

Previous Articles     Next Articles

Expression of integrin β1 in endochondral remodeling of rats

Chen Xiao, Yan Baoyong, Zuo Yanping, Sheng Haiying, Yuan Xuewei   

  1. Dept. of Orthodontics, The First Hospital of Hebei Medical Univercity, Shijiazhuang 050030, China
  • Received:2013-12-14 Revised:2014-02-11 Online:2014-07-01 Published:2014-07-01

RichHTML

2

PDF (PC)

564

Abstract:

Objective This study aims to investigate the expression of integrin β1(Itgβ1) in endochondral remodeling of rats and provide experiment basis to the regulation mechanism of the mandibular condylar cartilage. Methods A total of 60 male Sprague-Dawley rats were randomly divided into experimental and control groups. In the experimental group, inclined bite plate was cemented to the upper central incisors of the rats for 1 d. Five rats were executed in each group after 1, 3, 7, 14, 21, and 28 d. The specimens of the bilateral temporomandibular joints were subjected to hematoxylin–eosin staining and immunohistochemistry against Itgβ1. Data were presented as immunohistochemical scores(IHS). Results The IHS of Itgβ1 inthe experimental group was significantly higher than that inthe control group, whereasthe changes were normal. Conclusion Itgβ1 has a crucial function in the reconstruction of the condylar cartilage during mandibular forward positioning.

Key words: mandibular functional protrusion, adaptive remodeling of condylar cartilage, integrin β1, signal transduction

CLC Number: 

  • R 783.4

TrendMD: 
[1] Liu Runheng, Liu Yudong, Chen Zhuofan.. Role and mechanism of microRNA in osteogenic differentiation [J]. Inter J Stomatol, 2017, 44(1): 108-113.
[2] Geng Yuanming1, Shen Xiaoqing1, Xu Pingping2.. Effects of biological stress and mitogen-activated protein kinase on bone remodeling [J]. Inter J Stomatol, 2016, 43(6): 700-705.
[3] Xu Xin, Wang Yanmin,Bai Ding. Silent mating type information regulation 2 homolog 1 in bone and cartilage homeostasis [J]. Inter J Stomatol, 2016, 43(5): 569-572.
[4] Chen Tian, Bai Ding. Effect of sclerostin on cementogenesis and its mechanism [J]. Inter J Stomatol, 2016, 43(3): 333-337.
[5] Lin Ying, Qin Wei, Zou Rui, Lin Zhengmei. Regulation of mitogen-activated protein kinase in the odontoblast differentiation of dental pulp stem cells and pulp injury and reparation [J]. Inter J Stomatol, 2016, 43(3): 343-347.
[6] Xu Jinzhao1, Lan Jing2, Ji Ping2. Effect of frizzle in the wingless-type mice mammary tumor virus integration site family-frizzle signaling pathway [J]. Inter J Stomatol, 2016, 43(1): 85-.
[7] Tan Xiujun, Ye Ling, Wang Chenglin. Mechanisms of c-Jun N-terminal kinase signal transduction pathway regulating cell migration [J]. Inter J Stomatol, 2015, 42(5): 586-591.
[8] Zeng Suyun, Wang Jianguang. Effect of phosphatase and tensin homolog gene deleted on chromosome 10 in oral squamous cell carcinoma [J]. Inter J Stomatol, 2015, 42(3): 334-338.
[9] Meng Qingyang, Zheng Rong, Zhu Yang, Wang Dandan, Wu Lipeng, Sun Hongchen. Osteoclast differentiation factors and their signaling pathways [J]. Inter J Stomatol, 2015, 42(2): 189-193.
[10] Liu Yi, Chen Jianzhi.. Bone osteoinduction mechanism of Panax notoginseng saponins [J]. Inter J Stomatol, 2015, 42(1): 75-78.
[11] Zhang Jiaxi, Deng Hongyan, Ji Mingquan, Zhao Bingsong, Liu Dajun. Mechanism of action of erythropoietin and its receptor on osteoblasts [J]. Inter J Stomatol, 2015, 42(1): 102-105.
[12] Zhong Wenqun, Chen Gang, Zhao Yifang. Transforming growth factor β signaling pathway and its potential in regulating the components and functions of vascular vessels [J]. Inter J Stomatol, 2014, 41(6): 720-724.
[13] Li Li, Zheng Qian.. Transforming growth factor B3 in the development of palate [J]. Inter J Stomatol, 2014, 41(4): 440-443.
[14] Lü Linlin, Li Shu. Involvement of Yes-associated protein gene in tooth development [J]. Inter J Stomatol, 2013, 40(6): 760-763.
[15] Zheng Guiting, Xu Yan. Effects of the WNT/β-catenin signal transduction pathway on periodontal tissue regeneration [J]. Inter J Stomatol, 2013, 40(6): 773-777.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[7] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[8] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[9] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[10] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .