Int J Stomatol

Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (6): 770-774.doi: 10.3969/j.issn.1673-5749.2012.06.018

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Research progress on biological characteristics and testing means of Fusobacterium nucleatum

Guo Yang1, Zhang Yujie2, Xiao Shuiqing2.   

  1. 1. Dept. of Orthodontics, College of Stomatology, Binzhou Medical University, Binzhou 256603, China; 2. Dept. of Orthodontics, Jinan Stomatological Hospital, Jinan 250001, China
  • Received:2012-03-08 Revised:2012-07-13 Online:2012-11-01 Published:2012-11-01

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Abstract:

Fusobacterium nucleatum, one of the main pathogens causing periodontitis, is detected extremely high in oral and even systemic infectious diseases, and closely related to the clinical anaerobic infections. It indicates significant virulence or pathogenicity through multiple mechanisms to interfere with host defense capabilities and further lead to periodontal destructions. This article describes some important characteristics of Fusobacterium nucleatum, including its biological characteristics, classification, toxicity characteristics, as well as the major biological detection methods, and focuses on the application of polymerase chain reaction technology in the detection of Fusobacterium nucleatum.

Key words: Fusobacterium nucleatum, bacterial detection, polymerase chain reaction


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