窄谱强脉冲光治疗一期单侧唇裂术后瘢痕的疗效评价

doi:10.7518/gjkq.2023066

摘要/Abstract

摘要：

目的观察窄谱强脉冲光（DPL）治疗一期单侧唇裂术后瘢痕的疗效及安全性。方法选取2019年9月至2022年6月进行手术治疗的56例一期单侧唇裂患儿，按照随机数字表法分为A组和B组，各28例。2组患者均于拆线后第2天开始使用硅凝胶药物涂抹瘢痕至术后6个月；B组除涂抹药物外，在术后4、6、8周给予3次DPL治疗。分别于DPL治疗前、末次DPL治疗后、术后4个月、术后6个月时采用温哥华瘢痕量表（VSS）对瘢痕进行评估。末次随访时采用满意度调查表对家属满意度进行评价。记录治疗期间及末次治疗后１个月内的治疗相关不良事件，并进行统计学分析。结果两组患者在DPL治疗前VSS评分差异无统计学意义（P>0.05）；在末次DPL治疗后，B组VSS评分低于A组，差异有统计学意义（P<0.05）；术后4个月和6个月时，B组VSS评分低于A组，差异有统计学意义（P<0.05）。末次随访时，A组15例（占53.6%）对疗效表示非常满意，10例（占35.7%）表示满意，3例（占10.7%）表示一般；B组24例（85.7%）对疗效表示非常满意，4例（14.3%）表示满意。B组2例出现治疗后一过性色素沉着。结论窄谱强脉冲光可以有效治疗一期单侧唇裂术后瘢痕，患儿家属满意度高，不良反应少。

关键词: 窄谱强脉冲光, 一期单侧唇裂, 瘢痕, 温哥华瘢痕量表评分, 满意度

Abstract:

Objective To observe the effectiveness and safety of narrow-spectrum intense pulsed light (DPL) in the treatment of scar after surgery of primary unilateral cleft lip. Methods From September 2019 to June 2022, 56 children with primary unilateral cleft lip treated by surgery were selected. According to random number table, they were divided into group A and group B respectively, with 28 children in each group. Both groups began to use silicone gel drug to smear the scar on the second day after surgery until 6 months post-operation. Group B also taken three times DPL treatment at 4, 6 and 8 weeks post-operation. The scar was evaluated with Vancouver scar scale (VSS) before DPL treatment, after the last DPL treatment, 4 months after operation, and 6 months after operation. At the final follow-up, satisfaction questionnaire was used to evaluate the satisfaction of parents. The treatment-related adverse events during the DPL treatment pe-riod and within 1 month after the last treatment were recorded. The data was statistically analyzed. Results The difference of VSS scores between the two groups before DPL treatment was no significant (P>0.05). After the last DPL treatment, the VSS score of group B was lower than that of group A, with a statistically significant difference (P<0.05). At 4 months and 6 months post-operation, the VSS score of group B was lower than that of group A, the difference was statistically significant (P<0.05). At the final follow-up, 15 (53.6%) of group A were very satisfied with the efficacy, 10 (35.7%) were satisfied, and 3 (10.7%) were average; 24 (85.7%) of group B were very satisfied with the efficacy, and 4 (14.3%) were satisfied. Two patients in group B had transient pigmentation after treatment. Conclusion DPL can effectively treat the scar after primary unilateral cleft lip surgery, with high patient satisfaction and less adverse events.

Key words: narrow-spectrum intense pulsed light, primary unilateral cleft lip, scar, Vancouver scar scale score, satisfaction

中图分类号:

R 782.2+1

唐晓娟, 刘小静, 孙永恒, 张景霞. 窄谱强脉冲光治疗一期单侧唇裂术后瘢痕的疗效评价[J]. 国际口腔医学杂志, 2023, 50(4): 433-437.

Tang Xiaojuan, Liu Xiaojing, Sun Yongheng, Zhang Jingxia. Efficacy of narrow-spectrum intense pulsed light in the treatment of scar after surgery of primary unilateral cleft lip[J]. Int J Stomatol, 2023, 50(4): 433-437.

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