国际口腔医学杂志

国际口腔医学杂志 ›› 2018, Vol. 45 ›› Issue (5): 527-533.doi: 10.7518/gjkq.2018.05.006

• 种植专栏 • 上一篇    下一篇

钛种植体表面形貌对成骨的影响

祁星颖,郑国莹,隋磊()   

  1. 天津医科大学口腔医院修复科 天津 300070
  • 收稿日期:2017-12-20 修回日期:2018-06-04 出版日期:2018-09-01 发布日期:2018-09-20
  • 通讯作者: 隋磊
  • 作者简介:祁星颖,硕士,Email：653463840@qq.com

Effects of titanium implant surface topographies on osteogenesis

Xingying Qi,Guoying Zheng,Lei. Sui()   

  1. Dept. of Prosthodontics, Stomatological Hospital, Tianjin Medical University, Tianjin 300070, China
  • Received:2017-12-20 Revised:2018-06-04 Online:2018-09-01 Published:2018-09-20
  • Contact: Lei. Sui

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摘要：

钛种植体表面形貌是影响其周围骨结合的重要因素之一。目前,已有多种改性手段处理钛种植体表面以获得微米级形貌、纳米级形貌和分级微纳复合形貌。与未经改性处理的光滑表面相比,这些不同层级的粗糙表面形貌对种植体周围骨整合均有不同程度的促进作用。本文综述了钛种植体不同表面形貌的特点、制备方法及各自对成骨细胞黏附、增殖、分化等生物学行为的影响,为进一步优化设计以获得早期骨整合提供参考。

关键词: 钛种植体, 表面形貌, 微米级结构, 纳米级结构, 骨结合

Abstract:

The surface topography of titanium implants is one of the most important factors affecting implant-bone integration. At present, several methods, such as microtopography, nanotopography, and hierarchical hybrid microtopography/nanotopography, have been applied to modify titanium implant surfaces. These techniques promote implant osseointegration more extensively compared with smooth surfaces without modifications. The present study reviews different titanium implant surfaces, including their characteristics, modification methods, and effects on the adhesion, proliferation, and differentiation of osteoblasts. This work provides a reference for optimizing surface designs and achieving early osseointegration.

Key words: titanium implant, surface topography, microstructure, nanostructure, osseointegration

中图分类号: 

  • R783.3
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