国际口腔医学杂志

国际口腔医学杂志 ›› 2018, Vol. 45 ›› Issue (5): 522-526.doi: 10.7518/gjkq.2018.05.005

• 种植专栏 • 上一篇    下一篇

釉基质蛋白衍生物在口腔种植中的研究进展

米梦梦,夏海斌,王敏()   

  1. 武汉大学口腔医院种植科 武汉 430079
  • 收稿日期:2017-12-25 修回日期:2018-06-14 出版日期:2018-09-01 发布日期:2018-09-20
  • 通讯作者: 王敏 E-mail:83wangmin@whu.edu.cn
  • 作者简介:米梦梦,硕士,Email：mimeng1121@whu.edu.cn
  • 基金资助:
    国家自然科学基金(81500866)

Research progress on enamel matrix derivative in dental implantation

Mengmeng Mi,Haibin Xia,Min. Wang()   

  1. Dept. of Implantology, Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2017-12-25 Revised:2018-06-14 Online:2018-09-01 Published:2018-09-20
  • Contact: Min. Wang E-mail:83wangmin@whu.edu.cn
  • Supported by:
    This study was supported by National Natural Science Foundation of China(81500866)

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摘要：

釉基质蛋白衍生物是从幼猪牙胚中提取的釉基质蛋白的衍生物,具有促进牙周组织再生、诱导骨组织形成和生物矿化等生物学特性。目前,由于釉基质蛋白衍生物能够促进牙骨质的再生、新生牙周膜纤维功能性排列和新牙槽骨形成,主要应用于牙周疾病的治疗。在口腔种植方面,釉基质蛋白衍生物具有促进骨-种植体界面的骨结合、种植体周骨缺损的修复和种植体周围软组织的愈合等作用,在口腔种植中的应用也越来越多,本文就釉基质蛋白衍生物在口腔种植中的应用作一综述。

关键词: 釉基质蛋白衍生物, 牙种植, 硬组织, 软组织

Abstract:

Enamel matrix derivative comes from enamel matrix proteins, which are extracted from young pig tooth germ. The derivative can promote regeneration of periodontal tissues, bone induction, and biomineralization. At present, enamel matrix derivative is mainly used to treat periodontal diseases by promoting regeneration of new cementum, insertion of new functionally oriented periodontal ligament fibers, and formation of new alveolar bone. When used in dental implantation, enamel matrix derivative can promote osseointegration of bone-implant interfaces, repair of bone defects in implants, and healing of soft tissue around implants. As dental implantation is applied in increasingly wider settings, this article offers an overview of the use of enamel matrix derivative in dental implantation.

Key words: enamel matrix derivative, dental implantation, hard tissue, soft tissue

中图分类号: 

  • R783.3
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