国际口腔医学杂志 ›› 2018, Vol. 45 ›› Issue (2): 192-198.doi: 10.7518/gjkq.2018.02.012

• 综述 • 上一篇    下一篇

纳米羟磷灰石在牙体修复和牙髓治疗领域的应用

罗惟丹, 李明云, 周学东, 程磊   

  1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心
    四川大学华西口腔医院牙体牙髓病科 成都 610041
  • 收稿日期:2017-08-31 修回日期:2017-12-20 出版日期:2018-03-01 发布日期:2018-03-01
  • 通讯作者: 程磊,教授,博士,Email:chengleidentist@163.com
  • 作者简介:罗惟丹,硕士,Email:luowdan@163.com
  • 基金资助:
    国家国际科技合作专项项目(2014DFE30180)

Application of nano-hydroxyapatite in the clinical treatment of oral diseases

Luo Weidan, Li Mingyun, Zhou Xuedong, Cheng Lei   

  1. State Key Laboratory of Oral Diseases &National Clinical Research Center for Oral Diseases &Dept. of Conservative Dentistry and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2017-08-31 Revised:2017-12-20 Online:2018-03-01 Published:2018-03-01
  • Supported by:
    This study was supported by International Science and Technology Cooperation Program of China (2014DFE30180).

摘要: 纳米羟磷灰石与天然骨及牙釉质中的羟磷灰石晶体相似,具有良好的物理和化学性质、生物相容性、骨结合性等,在口腔疾病治疗领域应用广泛。本文对纳米羟磷灰石在牙体修复及牙髓治疗方面的相关研究进展进行综述,涉及牙科材料改性、再矿化、牙齿脱敏、牙髓治疗、牙髓组织工程学等方面。现有的研究表明,纳米羟磷灰石在口腔疾病治疗领域具有较大的潜力。

关键词: 纳米羟磷灰石, 材料改性, 再矿化, 脱敏, 牙髓治疗, 牙髓组织工程

Abstract: Nano-hydroxyapatite (nHA) shows a structure similar to that of hydroxyapatite crystal in human bone tissue and tooth enamel. Given its excellent physical and chemical properties, biocompatibility and osseointegration, nHA has been extensively applied in the clinical treatment of oral diseases. This article reviewed the most recent findings about nHA in stomatology, including the modification of restorative materials, tooth remineralization, tooth desensitization, pulp canal therapy and pulp tissue engineering. These studies are indicative of the future remarkable significance of nHA in stomatology.

Key words: nano-hydroxyapatite, material modification, remineralization, desensitization, pulp canal therapy, pulp tissue engineering

中图分类号: 

  • R781.05
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