Objective The purpose of the paper is to obtain the angle measurement data of facial soft tissues of Mongolian nationality and to establish the angle value database of human facial soft tissues of Mongolian and Han adults through studying their facial soft tissues with individual normal teeth occlusion in Inner Mongolia by using three-dimensional (3D) stereo photography technology. Methods A total of 295 normal dental occlusion samples were selected from students in Inner Mongolia, including 60 Han males, 90 Han females, 76 Mongolian females, and 69 Mongolian males. Using Morpheus 3D facial scanner, 14 soft tissue markers were identified, and 17 items were angled. SPSS 22.0 was used for statistical analysis and the comparisons of facial differences. Results Statistically significant differences were observed in facial shape angle (G-Sn-Pg), facial convex angle (N-Sn-Pg), total convex angle (N-Prn-Pg), nasolabial angle (Cm-Sn-Ls), SNPG angle (Pg-N-Ls), INPG angle (Pg-N-Li), Na angle (N-T-Prn), and Mn angle (Ls-T-Pg) between Han and Mongolian males. Statistically significant differences were noted in G-Sn-Pg, N-Sn-Pg, N-Prn-Pg, Pg-N-Ls, Pg-N-Li, mentolabial sulcus angle (Pg-Sm-Li), Mx angle (Ls-T-Pg), Ls-T-Pg, 1/3 of the face angle (Tri-T-N), and 1/3 of the middle face angle (N-T-Sn) between Han and Mongolian females. Statistically significant differences were observed in N-Sn-Pg, nasofrontal angle (G-N-Prn), Cm-Sn-Ls, Pg-N-Ls, Pg-Sm-Li, SNI angle (Ls-N-Li), TV angle (N-T-Pg), Ls-T-Prn, Ls-T-Pg, Tri-T-N, and N-T-Sn between Han females and Han males. In the Mongolian male-female comparison, the female’s N-Prn-Pg, G-N-Prn, nasal tip angle (N-Prn-Sn), and Tri-T-N are all larger than the male’s, whereas the male’s Sn-T-Me is larger than the female’s. Conclusion Some differences exist in the facial profile between Mongolian and Han populations in Inner Mongolia.