Int J Stomatol ›› 2019, Vol. 46 ›› Issue (3): 253-257.doi: 10.7518/gjkq.2019035

• Signalling Pathways • Previous Articles     Next Articles

Researches on interleukin-1α signalling pathway in tooth eruption

Mingmei Meng,Weihua Guo,Xuedong Zhou,Jing Zou()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2018-07-27 Revised:2019-02-25 Online:2019-05-01 Published:2019-06-05
  • Contact: Jing Zou E-mail:zoujing1970@126.com
  • Supported by:
    This study was supported by International Cooperation in Science and Technology Innovation/Cooperation Program in Science and Technology Innovation of Hong Kong, Macao and Taiwan, Science and Technology Department of Sichuan Province(2019YFH0025)

Abstract:

Tooth eruption, the process of the migration of the tooth crown from its site of development within bone to its functional position, is a complicated physiological course, involving alveolar bone, dental sac, osteoclasts, osteoblasts and multiple cytokines. Interleukin (IL)-1α is one of the dual-function cytokines which has a wide range of biological activities. This review is to address the researches on IL-1α signalling pathway in tooth eruption.

Key words: tooth eruption, interleukin-1α, dental sac

CLC Number: 

  • Q257

TrendMD: 
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