Int J Stomatol

Inter J Stomatol ›› 2007, Vol. 34 ›› Issue (05): 348-351.

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Relation between gene locus in chromosomes and mechanism of pathopoiesis of nonsyndromic cleft lip with or without palate

XU Bin, ZHOU Jing- lin, LI Wei.   

  1. Key. Laboratory of Oral Biomedical Engineering of Ministry of Education, Sichuan University, Chengdu 610041, China
  • Online:2007-09-20 Published:2007-09-20

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Abstract:

Nonsyndromic cleft lip with or without palate（NSCLP）, one of the most common congenital mal - formations, is a complex disease caused by genetic and environmental factors and their interactions. During the last two decades, scholars have discovered gene locus which have relation with NSCLP in many chromosomes. This review will briefly summarize the relation between gene locus in chromosomes and mechanism of pathopoiesis of NSCLP.

Key words: nonsyndromic cleft lip with or without palate, chromosome, gene locus


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