Int J Stomatol

Inter J Stomatol ›› 2016, Vol. 43 ›› Issue (3): 283-287.doi: 10.7518/gjkq.2016.03.007

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Influence of Porphyromonas gingivalis and its gingipain K in healthy gingiva of teenagers

Han Zhiqiang1, Bai Yang2, Xiao Shuiqing1, Sun Fei3, He Ping1   

  1. 1. Jinan Stomatological Hospital, Jinan 250001, China; 2. Dept. of Stomatology, The First People’s Hospital of Jinan, Jinan 250000, China; 3. Dept. of Orthodontics, Hospital of Stomatology, Binzhou Medical University, Binzhou 256603, China)
  • Received:2016-01-02 Revised:2016-02-22 Online:2016-05-01 Published:2016-05-01

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Abstract: Objective To explore the relationship of Porphyromonas gingivalis(P. gingivalis), gingipain K(Kgp) and puberty gingivitis in the subgingival. Methods Subjects(12-to 17-year-old children) included 50, 25, and 32 periodontally healthy, puberty gingivitis indexⅠ, and puberty gingivitis index Ⅱ children, respectively. 16S rDNA PCR was conducted to detect P. gingivalis and Kgp from the samples. Chi-square test was performed to compare the prevalence of Kgp and P. gingivalis in the three groups. Spearman correlation analysis was also employed to evaluate the relationship between the relative quantity of Kgp and periodontal parameters. Results P. gingivalis in the puberty gingivitis index Ⅱ group was higher than that in the periodontally healthy group. Puberty gingivitis index Ⅱ was higher than puberty gingivitis index Ⅰ and periodontally healthy groups. Puberty gingivitis index Ⅱ, puberty gingivitis index Ⅱ, and periodontally healthy groups were significantly different from one another(P<0.01). Puberty gingivitis index Ⅰ was also significantly different from puberty gingivitis index Ⅱ(P<0.05). Kgp in the puberty gingivitis index Ⅰ group is higher than that in the periodontally healthy group(P<0.01). Puberty gingivitis index Ⅱ is higher than puberty gingivitis index Ⅰ and periodontally healthy groups. Puberty gingivitis index Ⅰ(P<0.05) and puberty gingivitis index Ⅱ(P<0.01) are significantly different from the periodontally healthy group. P. gingivalis and Kgp detection rates increased in the gingivitis index. Conclusion Kgp and P. gingivalis are closely related to puberty gingivitis in the subgingival.

Key words: teenagers, Porphyromonas gingivalis, gingipain K, gingivitis, teenagers, Porphyromonas gingivalis, gingipain K, gingivitis

CLC Number: 

  • R 788

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[1] Imamura T. The role of gingipains in the pathogenesis of periodontal disease[J]. J Periodontol, 2003, 74(1):111-118.
[2] Beikler T, Peters U, Ehmke B, et al. Sequence analysis of Kgp in Porphyromonas gingivalis isolates from periodontitis patients[J]. Oral Microbiol Immunol, 2003, 18(6):393-397.
[3] Alexander SA. Effects of orthodontic attachments on the gingival health of permanent second molars[J]. Am J Orthod Dentofacial Orthop, 1991, 100(4):337-340.
[4] Bhat M. Periodontal health of 14-17-year-old US schoolchildren[J]. J Public Health Dent, 1991, 51(1):5-11.
[5] Masunaga H, Tsutae W, Oh H, et al. Use of quantitative PCR to evaluate methods of bacteria sampling in periodontal patients[J]. J Oral Sci, 2010, 52(4):615-621.
[6] Haffajee AD, Socransky SS. Microbial etiological agents of destructive periodontal diseases[J]. Periodontol 2000, 1994, 5:78-111.
[7] Lamell CW, Griffen AL, McClellan DL, et al. Acquisition and colonization stability of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in children[J]. J Clin Microbiol, 2000, 38(3):1196-1199.
[8] Ozmeri? N, Preus NR, Olsen I. Genetic diversity of Porphyromonas gingivalis and its possible importance to pathogenicity[J]. Acta Odontol Scand, 2000, 58(4):183-187.
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