Inter J Stomatol ›› 2013, Vol. 40 ›› Issue (4): 429-431.doi: 10.7518/gjkq.2013.04.003
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Chen Yi, Tao Renchuan, Lin Xuefang, Liu Zhenmin, Yong Xiangzhi, Li Runying.
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Objective To detect the human neutrophil peptide 1-3(HNP1-3) expression in circadian rhythm. Methods Saliva, peripheral venous blood and gingival crevicular fluid(GCF) samples from mesio-buccal gingival crevice of four first molars of six healthy individuals were collected at two consecutive days from 6∶00 to 22∶00, and the expression of HNP1-3 was detected by enzyme-linked immunosorbent assay(ELISA) method. Results The median in GCF was 5.86 μg·L-1, the overall trend was a sinusoidal waveform, with peak at 14∶00 and valley at 20∶00. The median in saliva was 2.15 μg·L-1, the overall trend was the “V” word waveform, higher in the morning and evening, the valley at 14∶00. The median in peripheral venous blood was 4.79 μg·L-1, the overall trend was single peak waveform, reaching a peak from 6∶00 to 10∶00, and then declining slowly. Conclusion The expression HNP1-3 in saliva, GCF, peripheral venous blood samples existed differences. The trend from high to low was GCF, blood, saliva and showed a certain circadian rhythm.
Key words: circadian rhythm, human neutrophil peptide, gingival crevicular fluid, peripheral venous blood
Chen Yi, Tao Renchuan, Lin Xuefang, Liu Zhenmin, Yong Xiangzhi, Li Runying.. The circadian rhythm expression of the human neutrophil peptide 1-3[J].Int J Stomatol, 2013, 40(4): 429-431.
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https://www.gjkqyxzz.cn/EN/Y2013/V40/I4/429
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