Inter J Stomatol ›› 2012, Vol. 39 ›› Issue (5): 604-607.doi: 10.3969/j.issn.1673-5749.2012.05.013

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Head and neck cancer stem cells’surface markers and their sorting

Xu Xiaorong1, Jia Jun1,2, Zhang Wenfeng2.   

  1. 1. The State Key Laboratory Breeding Base of Basic Science of Stomatology(Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, China; 2. Dept. of Oral and Maxillofacial Surgery, Hospital of Stomatology, Wuhan University, Wuhan 430079, China
  • Received:2011-10-22 Revised:2012-05-03 Online:2012-09-01 Published:2012-09-01

Abstract:

Increasing data showed head and neck cancer stem cells were responsible for head and neck cancer on carcinogenesis, relapse, metastasis and drug resistance. The purpose of this review is to provide a summary on research progress of specific surface stem cell markers in head and neck cancer stem cells and their sorting.

Key words: cancer stem cell, surface marker, in vitro separation method, fluorescence activated cell soring, magnetic activated cell sorting, side population cell sorting


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