国际口腔医学杂志 ›› 2026, Vol. 53 ›› Issue (1): 84-90.doi: 10.7518/gjkq.2026005
Keer Chen(
),Jiaqi Bao,Weilian Sun(
)
摘要:
牙周炎是成年患者拔牙的常见原因之一。拔牙后牙槽窝常伴骨吸收,进而影响后续的种植修复效果。牙槽嵴保存术是在拔牙同期将生物材料植入拔牙窝内的骨增量手术,有助于延缓牙槽骨吸收、恢复牙槽嵴的美观与功能。与非牙周炎拔牙窝相比,牙周炎拔牙窝的愈合过程更复杂多变,其中颊侧骨壁形态对拔牙窝愈合后的骨组织线性和体积变化、软组织量改变及组织学特征具有重要影响。本文针对不同颊侧骨壁形态影响牙周炎拔牙位点牙槽嵴保存术的应用进行总结与分析,发现颊壁厚者较薄者减缓牙槽骨吸收效果更为明显,颊壁缺损位点较完整位点需要额外的软硬组织增量手术,为不同适应证下的牙槽嵴保存术式选择提供了诊疗思路。
中图分类号:
| [1] | Passarelli PC, Pagnoni S, Piccirillo GB, et al. Reasons for tooth extractions and related risk factors in adult patients: a cohort study[J]. Int J Environ Res Public Health, 2020, 17(7): 2575. |
| [2] | Broers DLM, Dubois L, de Lange J, et al. Reasons for tooth removal in adults: a systematic review[J]. Int Dent J, 2022, 72(1): 52-57. |
| [3] | 赖思煜, 侯建霞. 牙槽嵴保存在非牙周炎与牙周炎患牙拔牙位点的应用进展[J]. 中华口腔医学杂志, 2020, 55(4): 266-270. |
| Lai SY, Hou JX. Progress in the application of al-veolar ridge preservation at extraction sites in non-periodontitis and periodontitis patients[J]. Chin J Stomatol, 2020, 55(4): 266-270. | |
| [4] | Sculean A, Stavropoulos A, Bosshardt DD. Self-regenerative capacity of intra-oral bone defects[J]. J Clin Periodontol, 2019, 46(): 70-81. |
| [5] | Hämmerle CHF, Araújo MG, Simion M, et al. Evidence-based knowledge on the biology and treatment of extraction sockets[J]. Clin Oral Implants Res, 2012, 23(): 80-82. |
| [6] | 胡文杰. 牙槽嵴保存术的临床实施问题探讨[J]. 国际口腔医学杂志, 2021, 48(3): 249-258. |
| Hu WJ. Related problems in clinical practice of alveolar ridge preservation[J]. Int J Stomatol, 2021, 48(3): 249-258. | |
| [7] | Wei YP, Xu T, Hu WJ, et al. Socket preservation following extraction of molars with severe periodontitis[J]. Int J Periodontics Restorative Dent, 2021, 41(2): 269-275. |
| [8] | Monje A, Pons R, Roccuzzo A, et al. Reconstructive therapy for the management of peri-implantitis via submerged guided bone regeneration: a prospective case series[J]. Clin Implant Dent Relat Res, 2020, 22(3): 342-350. |
| [9] | Engler-Hamm D, Cheung WS, Yen A, et al. Ridge preservation using a composite bone graft and a bioabsorbable membrane with and without primary wound closure: a comparative clinical trial[J]. J Pe-riodontol, 2011, 82(3): 377-387. |
| [10] | Canullo L, Del Fabbro M, Khijmatgar S, et al. Dimensional and histomorphometric evaluation of biomaterials used for alveolar ridge preservation: a systematic review and network meta-analysis[J]. Clin Oral Investig, 2022, 26(1): 141-158. |
| [11] | Mercado F, Vaquette C, Hamlet S, et al. Enamel matrix derivative promotes new bone formation in xenograft assisted maxillary anterior ridge preserva-tion-a randomized controlled clinical trial[J]. Clin Oral Implants Res, 2021, 32(6): 732-744. |
| [12] | Araújo MG, Lindhe J. Dimensional ridge alterations following tooth extraction. An experimental study in the dog[J]. J Clin Periodontol, 2005, 32(2): 212-218. |
| [13] | Covani U, Ricci M, Bozzolo G, et al. Analysis of the pattern of the alveolar ridge remodelling follo-wing single tooth extraction[J]. Clin Oral Implants Res, 2011, 22(8): 820-825. |
| [14] | Chappuis V, Araújo MG, Buser D. Clinical relevance of dimensional bone and soft tissue alterations post-extraction in esthetic sites[J]. Periodontol 2000, 2017, 73(1): 73-83. |
| [15] | Januário AL, Duarte WR, Barriviera M, et al. Dimension of the facial bone wall in the anterior ma-xilla: a cone‐beam computed tomography study[J]. Clin Oral Implants Res, 2011, 22(10): 1168‐1171. |
| [16] | Couso-Queiruga E, Stuhr S, Tattan M, et al. Post-extraction dimensional changes: a systematic review and meta-analysis[J]. J Clin Periodontol, 2021, 48(1): 126-144. |
| [17] | Cardaropoli D, Tamagnone L, Roffredo A, et al. Relationship between the buccal bone plate thickness and the healing of postextraction sockets with/without ridge preservation[J]. Int J Periodontics Resto-rative Dent, 2014, 34(2): 211-217. |
| [18] | Castro AB, van Dessel J, Temmerman A, et al. Effect of different platelet-rich fibrin matrices for ridge preservation in multiple tooth extractions: a split-mouth randomized controlled clinical trial[J]. J Clin Periodontol, 2021, 48(7): 984-995. |
| [19] | Tu CC, Zheng ZC, Cheng NC, et al. Alveolar mucosal cell spheroids promote extraction socket healing and osseous defect regeneration[J]. J Periodontol, 2024, 95(4): 372-383. |
| [20] | Bighetti ACC, Cestari TM, Paini S, et al. Efficacy and safety of a new heterologous fibrin biopolymer on socket bone healing after tooth extraction: an experimental pre-clinical study[J]. J Clin Periodontol, 2024, 51(8): 1017-1033. |
| [21] | Wei YP, Xu T, Zhao LP, et al. Ridge preservation in maxillary molar extraction sites with severe perio-dontitis: a prospective observational clinical trial[J]. Clin Oral Investig, 2022, 26(3): 2391-2399. |
| [22] | Zhao LP, Wei YP, Xu T, et al. Changes in alveolar process dimensions following extraction of molars with advanced periodontal disease: a clinical pilot study[J]. Clin Oral Implants Res, 2019, 30(4): 324-335. |
| [23] | Kim JJ, Ben Amara H, Chung I, et al. Compromised extraction sockets: a new classification and prevalence involving both soft and hard tissue loss[J]. J Periodontal Implant Sci, 2021, 51(2): 100-113. |
| [24] | Ben Amara H, Kim JJ, Kim HY, et al. Is ridge pre-servation effective in the extraction sockets of perio-dontally compromised teeth? A randomized controlled trial[J]. J Clin Periodontol, 2021, 48(3): 464-477. |
| [25] | Tien HK, Lee WH, Kim CS, et al. Alveolar ridge regeneration in two-wall-damaged extraction sockets of an in vivo experimental model[J]. Clin Oral Implants Res, 2021, 32(8): 971-979. |
| [26] | Araújo MG, Dias DR, Matarazzo F. Anatomical characteristics of the alveolar process and basal bone that have an effect on socket healing[J]. Perio-dontol 2000, 2023, 93(1): 277-288. |
| [27] | Chen ST, Darby I. The relationship between facial bone wall defects and dimensional alterations of the ridge following flapless tooth extraction in the anteriormaxilla[J]. Clin Oral Implants Res, 2017, 28(8): 931-937. |
| [28] | Kim JH, Koo KT, Capetillo J, et al. Periodontal and endodontic pathology delays extraction socket hea-ling in a canine model[J]. J Periodontal Implant Sci, 2017, 47(3): 143-153. |
| [29] | Ahn JJ, Shin HI. Bone tissue formation in extraction sockets from sites with advanced periodontal di-sease: a histomorphometric study in humans[J]. Int J Oral Maxillofac Implants, 2008, 23(6): 1133-1138. |
| [30] | Kim JJ, Ben Amara H, Schwarz F, et al. Is ridge preservation/augmentation at periodontally compromised extraction sockets safe? A retrospective study[J]. J Clin Periodontol, 2017, 44(10): 1051-1058. |
| [31] | Yang F, Ruan Y, Bai XL, et al. Alveolar ridge preservation in sockets with severe periodontal destruction using autogenous partially demineralized dentin matrix: a randomized controlled clinical trial[J]. Clin Implant Dent Relat Res, 2023, 25(6): 1019-1032. |
| [32] | Zhang HY, Wei YP, Xu T, et al. Assessment of soft and hard tissue characteristics of ridge preservation at molar extraction sites with severe periodontitis: a randomized controlled trial[J]. BMC Oral Health, 2022, 22(1): 511. |
| [33] | Zhang HY, Xu T, Wei YP, et al. Assessment of soft and hard tissue changes following micro crestal flap-alveolar ridge preservation and augmentation at molar extraction sites in patients with stage Ⅲ/Ⅳ perio-dontitis: a randomized controlled trial[J]. J Clin Pe-riodontol, 2024, 51(10): 1311-1322. |
| [34] | Dai AN, Li HY, Kang S, et al. Effect of alveolar ridge preservation at periodontally compromised molar extraction sockets: a retrospective cohort study[J]. J Periodontol, 2025, 96(1): 9-20. |
| [35] | Fok MR, Pelekos G, Jin LJ. Efficacy of alveolar ridge preservation in periodontally compromised molar extraction sites: a systematic review and meta analysis[J]. J Clin Med, 2024, 13(5): 1198. |
| [36] | Ikawa T, Akizuki T, Ono W, et al. Ridge reconstruction in damaged extraction sockets using tunnel β- tricalcium phosphate blocks: a 6-month histological study in beagle dogs[J]. J Periodontal Res, 2020, 55(4): 496-502. |
| [37] | Barone A, Toti P, Quaranta A, et al. Clinical and histological changes after ridge preservation with two xenografts: preliminary results from a multicentre randomized controlled clinical trial[J]. J Clin Perio-dontol, 2017, 44(2): 204-214. |
| [38] | Steigmann L, Di Gianfilippo R, Steigmann M, et al. Classification based on extraction socket buccal bone morphology and related treatment decision tree[J]. Materials, 2022, 15(3): 733. |
| [39] | Avila-Ortiz G, Chambrone L, Vignoletti F. Effect of alveolar ridge preservation interventions following tooth extraction: a systematic review and meta-ana-lysis[J]. J Clin Periodontol, 2019, 46(): 195-223. |
| [40] | Couso-Queiruga E, Weber HA, Garaicoa-Pazmino C, et al. Influence of healing time on the outcomes of alveolar ridge preservation using a collagenated bovine bone xenograft: a randomized clinical trial[J]. J Clin Periodontol, 2023, 50(2): 132-146. |
| [41] | Cosyn J, Cleymaet R, de Bruyn H. Predictors of alveolar process remodeling following ridge preservation in high-risk patients[J]. Clin Implant Dent Relat Res, 2016, 18(2): 226-233. |
| [42] | Seyssens L, Eghbali A, Christiaens V, et al. A one-year prospective study on alveolar ridge preservation using collagen-enriched deproteinized bovine bone mineral and saddle connective tissue graft: a cone beam computed tomography analysis[J]. Clin Implant Dent Relat Res, 2019, 21(5): 853-861. |
| [43] | Barone A, Ricci M, Romanos GE, et al. Buccal bone deficiency in fresh extraction sockets: a prospective single cohort study[J]. Clin Oral Implants Res, 2015, 26(7): 823-830. |
| [44] | Zhou X, Yang J, Wu L, et al. Evaluation of the effect of implants placed in preserved sockets versus fresh sockets on tissue preservation and esthetics: a meta-analysis and systematic review[J]. J Evid Ba-sed Dent Pract, 2019, 19(4): 101336. |
| [45] | Ko YC, Lee D, Kwon O, et al. Preclinical comparison study of experimental peri-implantitis between alveolar ridge preservation and spontaneous healing sites in infected and noninfected tooth: a randomi-zed blinded in vivo study[J]. J Periodontol, 2024, 95(10): 977-990. |
| [1] | 石琦企,秦旭,朱光勋. 铜死亡在牙周炎中的研究进展[J]. 国际口腔医学杂志, 2026, 53(1): 91-97. |
| [2] | 王诗雅,袁国华,邹静. 异位釉质的形成机制及临床诊疗策略[J]. 国际口腔医学杂志, 2025, 52(6): 713-721. |
| [3] | 陈禹黄,梁星,李然. 牙周炎患者缺失牙修复的临床考量及预后评估[J]. 国际口腔医学杂志, 2025, 52(6): 823-831. |
| [4] | 朱然,严静,孙卫斌,吴文蕾,刘玉. 服用抗血栓药物患者牙周基础治疗期间的出血风险管理[J]. 国际口腔医学杂志, 2025, 52(5): 670-676. |
| [5] | 李欢,原韶钟. 牙周炎与非酒精性脂肪性肝病相关性的研究进展[J]. 国际口腔医学杂志, 2025, 52(5): 677-683. |
| [6] | 祝舒钰,周静,谢志刚. 辅助性T细胞17与调节性T细胞之间的制衡效应调控口腔颌面部骨损伤修复的研究进展[J]. 国际口腔医学杂志, 2025, 52(4): 514-525. |
| [7] | 于寰,康健. 牙周内镜在口腔临床诊疗中的应用进展[J]. 国际口腔医学杂志, 2025, 52(4): 544-551. |
| [8] | 李天元, 朱彤欣, 柳庆, 董迎春, 陈斌. 间充质干细胞用于牙周再生临床疗效的系统评价与Meta分析[J]. 国际口腔医学杂志, 2025, 52(3): 296-307. |
| [9] | 别梦瑶,周婕妤,吴亚菲,赵蕾. 牙龈卟啉单胞菌影响血管平滑肌细胞调节性细胞死亡及表型转换的研究进展[J]. 国际口腔医学杂志, 2025, 52(3): 308-316. |
| [10] | 范兴丽,潘乐,赵家园,项秋猛,陈启林. 竞争性内源性RNA在牙周炎中的作用及机制的研究进展[J]. 国际口腔医学杂志, 2025, 52(3): 317-322. |
| [11] | 赵美林,赵依琼,黄姣. Ⅲ期C级牙周炎正畸患者上前牙龈乳头缺陷伴牙龈退缩1例[J]. 国际口腔医学杂志, 2025, 52(3): 333-340. |
| [12] | 李晶,康健. 牙周微创手术中再生材料选择及疗效的研究进展[J]. 国际口腔医学杂志, 2025, 52(2): 161-168. |
| [13] | 张潇月,陈舒泽,周婕妤,程磊,赵蕾. 具核梭杆菌经铁死亡途径破坏体外肠道上皮屏障模型的研究[J]. 国际口腔医学杂志, 2025, 52(2): 183-194. |
| [14] | 钟良军. 数字化技术在重度牙周炎治疗中的应用[J]. 国际口腔医学杂志, 2025, 52(1): 1-10. |
| [15] | 程守正,李太文,赵蕾. 血清淀粉样蛋白A与牙周炎相关性的研究进展[J]. 国际口腔医学杂志, 2025, 52(1): 117-122. |
|
||