国际口腔医学杂志 ›› 2021, Vol. 48 ›› Issue (5): 549-555.doi: 10.7518/gjkq.2021084
Xu Lin(),Wang Ruyi,Gou Xinrui,Wang Xiaoli,Li Yu(
)
摘要:
下颌髁突软骨(MCC)不同于生长板和身体其他部位的关节软骨,属于继发性纤维软骨,是颞下颌关节的重要组成部分。由于下颌骨附有牙齿行使咀嚼功能的特殊性,MCC在一生中受机械刺激影响不断改建,随年龄增长可能发生退行性变。甲状旁腺激素相关蛋白(PTHrP)最早在恶性体液性高钙血症中发现,在许多组织中以旁分泌或者自分泌的方式发挥调节骨代谢的作用,在MCC的发育、改建和退行性变中具有重要意义。本文就PTHrP在MCC中的作用进行阐述,为PTHrP在正畸功能矫形和颞下颌关节修复再生提供思路和研究方向。
中图分类号:
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