Int J Stomatol

Int J Stomatol ›› 2025, Vol. 52 ›› Issue (4): 552-558.doi: 10.7518/gjkq.2025074

• Reviews • Previous Articles    

Research progress on the effects of maternal oral microorganisms on neonatal oral and systemic health

Hanzhi Deng(),Lei Zhao()   

  1. State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Dept. of Periodontology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2024-05-09 Revised:2024-08-20 Online:2025-07-01 Published:2025-06-20
  • Contact: Lei Zhao E-mail:1327726675@qq.com;jollyzldoc@163.com
  • Supported by:
    Natural Science Foundation of Sichuan Province(2023NSFSC0553)

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Abstract:

The influence of maternal oral health on pregnancy outcomes (such as preterm low birth weight, preeclampsia, and stillbirth) has been widely concerned by scholars. With the detection of oral microorganisms in the placenta, amnio-tic fluid, and other maternal structures, the influence and possible mechanism of oral microorganisms in pregnant women on the colonization of the fetus in the womb; the shaping of the fetal immune system; and the subsequent oral health of the newborn have become a new research hotspot. In this study, the effects of maternal oral microbiota on fetal health neonatal oral microbiota were reviewed. The maternal oral microbiota may influence oral health through the colonization and succession of oral microbiota during early life and may regulate fetal development, which has a profound impact on systemic health.

Key words: newborn, pregnant women, oral microorganism, microbial colonization in utero, early life microorganis

CLC Number: 

  • R780.2

TrendMD: 
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