Int J Stomatol

Inter J Stomatol ›› 2016, Vol. 43 ›› Issue (4): 421-427.doi: 10.7518/gjkq.2016.04.013

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Research progress on the mechanism of epithelial-mesenchymal transition in salivary adenoid cystic carcinoma

Wu Jiashun, Tang Yaling   

  1. State Key Laboratory of Oral Diseases, Dept. of Oral Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Online:2016-07-01 Published:2016-07-01

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Abstract: Salivary adenoid cystic carcinoma(SACC) is one of the most malignant tumors in salivary adenoid tissue with a feature of perineural invasion, lung metastasis, which grows slowly but easily trends to invasion and has a poor prognosis. In recent years domestic and foreign scholars have done a lot of researches about epithelial-mesenchymal transition(EMT) in SACC, for revealing the mechanism of its development, invasion and metastasis and exposing new therapy. This review elucidated the EMT mechanism in SACC.

Key words: salivary adenoid cystic carcinoma, epithelial-mesenchymal transition, regulating mechanism


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