Int J Stomatol

Inter J Stomatol ›› 2010, Vol. 37 ›› Issue (6): 732-736.doi: 10.3969/j.issn.1673-5749.2010.06.031

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Secreted aspartic proteinase genes differential expression and influencing factors

GE Yan-ping1, HU Yan2.   

  1. （1. Research Institute of Stomatology, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou 510055, China; 2. Dept. of Oral Biology, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou 510055, China）
  • Online:2010-11-20 Published:2010-11-20

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Abstract:

The secreted aspartic proteinases（SAP）, encoded by the sap gene family, appear to play a major role in Saccharomyces albicans（S.albicans） virulence. The sap gene family is differentially regulated, and distinct members are expressed under a variety of laboratory growth conditions and during experimental S.albicans infections in vitro and in vivo. This review is to summarize recent research regarding the structural feature of Sap, the sap gene family differential expression and discuss the influencing factors.

Key words: Saccharomyces albicans, secreted aspartic proteinase gene, expression


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