Int J Stomatol

Int J Stomatol ›› 2022, Vol. 49 ›› Issue (1): 60-65.doi: 10.7518/gjkq.2022011

• Orginal Article • Previous Articles     Next Articles

Value research on differential diagnosis of pleomorphic adenomas and adenolymphoma by histogram analysis of ultrasound gray

Xia Feifei(),Qin Wenjuan,Feng Jia,Zhou Xuyang,Sun Ercan,Li Changxue()   

  1. Dept. of Stomatology, First Affiliated Hospital, School of Medicine, Shihezi University, Shihezi 832008, China
  • Received:2021-04-12 Revised:2021-09-22 Online:2022-01-01 Published:2022-01-07
  • Contact: Changxue Li E-mail:1400977438@qq.com;3541226598@qq.com

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Abstract: Objective To investigate the value of gray-scale histogram in the differential diagnosis of pleomorphic Adenoma and Adenolymphoma of parotid gland.Methods The preoperative ultrasound images of 18 patients with pleomorphic Adenoma (PA) , and 13 patients with Adenolymphoma (AL) were analyzed for imaging gray-scale histograms parameters (mean, variance, skewness, Kurtosis, 1st, 10th, 50th, 90th, 99th percentiles).The Receiver Operating Characteristic (ROC) curve was used to calculate the differential diagnostic efficiency of each parameter.Results The variance of PA group was higher than that of AL group, but the skewness and kurtosis were lower than that of AL group, and the difference was statistically significant (P<0.05). The value of mean, the 1st, 10th, 50th, 90th and 99th percentiles between the two group had no significant difference (P>0.05). The analysis of ROC curve showed that the Kurtosis was the most effective parameter for differential diagnosis. The AUC was 0.744 (P=0.022), the best critical value was 1.71, the sensitivity was 76.9%, the specificity was 61.1%, and the yoden index was 0.380. Besides, The AUC, optimal critical value, sensitivity, specificity and Yoden index of variance were 0.735 (P=0.028), 864.94, 72.2%, 76.9% and 0.491 respectively.Conclusion The ultrasonic gray histogram has a certain value in the differential diagnosis between PA and Al.

Key words: pleomorphic adenoma, adenolymphoma, histogram, ultrasonic gray scale, ultrasonic examination


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Fig 1

Pleomorphic adenoma of right parotid gland"

Fig 2

Adenolymphoma of right parotid gland"

Tab 1

Comparison of gray histogram parameters between PA and AL"

参数 PA组 AL组 t/z值 P值
均值 43.14（25.99、59.01）* 23.08（19.19、54.73）* -1.601 0.109
方差 1072.75±391.14 755.72±263.39 2.531 0.017
偏度 1.10±0.64 1.82±1.12 -2.269 0.031
峰度 1.55（0.60、3.43）* 3.94（1.64、7.85）* -2.282 0.022
第1百分位数 1（1、1）* 1（1、2）* -1.844 0.065
第10百分位数 1.5（1、1.5）* 1（1、19.5）* -0.285 0.776
第50百分位数 33（15.5、54.5）* 13（4、52.5）* -1.502 0.133
第90百分位数 85.83±29.24 71.23±28.78 1.381 0.178
第99百分位数 138.06±32.72 12.00±26.95 1.629 0.114

Fig 3

The ROC curve for differential diagnosis of PA and AL"

Fig 4

The ROC curve of skewness and kurtosis in differential diagnosis PA and AL"

Tab 2

ROC curve analysis results of histogram discrimination between PA and AL"

参数 AUC P值 临界值 敏感度 特异度 约登指数
方差 0.735 0.028 864.94 0.722 0.769 0.491
偏度 0.705 0.055 1.949 0.462 0.994 0.406
峰度 0.744 0.022 1.710 0.769 0.611 0.380
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