Inter J Stomatol ›› 2018, Vol. 45 ›› Issue (3): 276-279.doi: 10.7518/gjkq.2018.03.006

• Stem Cell • Previous Articles     Next Articles

Immune regulation of dental stem cells

Zhang Xiangyi, Liu Yali   

  1. Dept. of Orthodontics, Stomatological Hospital of Kunming Medical University, Kunming 650032, China
  • Received:2017-04-08 Revised:2017-10-12 Published:2018-05-08
  • Supported by:
    This study was supported by National Natural Science Foundation of China (31301067), Research Fund of The Ministry of Education’s Doctoral Programs (20135317120005) and Yunnan Provincial Education Department Scientific Research Fund (2013Z106).

Abstract: Dental stem cell (DSC) is a type of stem cells that possess unique immunomodulation properties and can be effectively obtained from isolated dental or periodontal tissue. They exert immunosuppressive effects through direct contact or secretion of cytokines and play a key role in the proliferation, differentiation, and apoptosis of T cells, B cells, and other lymphocytes. The treatment of a variety of chronic inflammatory and autoimmune diseases has a certain clinical significance. In this review, we summarize current studies on the immunomodulatory properties of several common DSCs.

Key words: dental stem cell, immunomodulation, stem cell therapy

CLC Number: 

  • R392

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