Int J Stomatol

Inter J Stomatol ›› 2013, Vol. 40 ›› Issue (4): 533-536.doi: 10.7518/gjkq.2013.04.035

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Research progress on extracellular DNA release by Streptococcus gordonii

Liu Min, Wang Lin, Hao Yuqing, Liu Yaling.   

  1. State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2012-09-17 Revised:2013-03-18 Online:2013-07-01 Published:2013-07-01

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Abstract:

Bacterial extracellular DNA（eDNA） is an important component of extracellular biofilm matrix. It can stable cell-cell adhesion and biofilm structure, and can transfer the genetic information. DNA release is typically a consequence of cell lysis. Streptococcus gordonii can release eDNA through a special hydrogen peroxide-dependent mechanism. This review will summarize the recent research progress on characteristics of eDNA release by Streptococcus gordonii and its release effect.

Key words: extracellular DNA, Streptococcus gordonii, releasing mechanism, hydrogen peroxide


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