国际口腔医学杂志

国际口腔医学杂志 ›› 2025, Vol. 52 ›› Issue (2): 176-182.doi: 10.7518/gjkq.2025041

• 材料学专栏 • 上一篇    下一篇

牙齿漂白材料的研究新进展

苏晓凡1,2(),刘素汝1,2,胡兴宇1,2,刘磊1,2,田卫东1,2,谢利1()   

  1. 1.口腔疾病防治全国重点实验室;国家口腔医学中心 国家口腔疾病临床医学研究中心;口腔转化医学教育部工程研究中心 口腔再生医学国家地方联合工程实验室 成都 610041
    2.口腔疾病防治全国重点实验室;国家口腔医学中心 国家口腔疾病临床医学研究中心;四川大学华西口腔医院创伤整形外科 成都 610041
  • 收稿日期:2024-08-17 修回日期:2024-12-16 出版日期:2025-03-01 发布日期:2025-03-01
  • 通讯作者: 谢利
  • 作者简介:苏晓凡，住院医师，硕士，Email：steafan2020@163.com
  • 基金资助:
    国家自然科学基金(32271415);国家重点研发计划(2022YFA1104400);四川省自然科学基金(2023NSFSC0561);四川省科技支撑项目(2022YFS0283)

Recent progress in research on tooth bleaching materials

Xiaofan Su1,2(),Suru Liu1,2,Xingyu Hu1,2,Lei Liu1,2,Weidong Tian1,2,Li Xie1()   

  1. 1.State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Engineering Research Center of Oral Translational Medicine, Ministry of Education ＆ National Engineering Laboratory for Oral Regenerative Medicine, Chengdu 610041, China
    2.State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Dept. of Traumatic and Plastic Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2024-08-17 Revised:2024-12-16 Online:2025-03-01 Published:2025-03-01
  • Contact: Li Xie
  • Supported by:
    National Natural Science Foundation of China(32271415);National Key R&D Program of China(2022YFA1104400);Natural Science Foundation of Sichuan Province(2023NSFSC0561);Program of Department of Science and Technology of Sichuan Province(2022YFS0283)

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摘要：

目前临床应用的牙齿漂白材料主要以过氧化氢作为功能成分。为达到有效的漂白效果，通常需要使用高浓度过氧化氢或较长的接触时间。然而，高浓度过氧化氢或长接触时间常导致牙齿敏感、釉质损伤、软组织损伤等不良反应，这极大地限制了牙齿漂白材料的临床应用。近年来，以产生大量强氧化性自由基或者活性氧为特点的高级氧化技术飞速发展，为研发新型牙齿漂白材料提供了新策略和新方法，可望提高牙齿漂白的治疗效果并减少或避免其并发症。本文系统性地总结了牙齿漂白材料的研究新进展，着重介绍其种类、作用机制、有效性和安全性评价结果。同时，也对研究中存在的不足以及未来发展方向进行了评述。

关键词: 牙齿漂白材料, 高级氧化技术, 类芬顿反应, 光催化, 压电催化

Abstract:

Hydrogen peroxide is the primary functional component in tooth bleaching materials in clinical applications. Achieving effective bleaching outcomes typically necessitates the use of high concentrations of hydrogen peroxide or prolonged contact times. However, the application of high concentrations or prolonged contact times often results in adverse effects, such as tooth sensitivity, enamel damage, and soft tissue irritation, significantly constraining the clinical utility of tooth bleaching materials. In recent years, advanced oxidation processes have rapidly developed and are characterized by the generation of numerous strong oxidative free radicals or reactive oxygen species. This advancement provides new strategies and methods for the formulation of innovative tooth bleaching mate-rials to improve therapeutic effects while minimizing or avoiding associated complications. This article systematically reviews the research progress of novel tooth bleaching materials and presents results from assessments of material effectiveness and safety. Additionally, the article addresses existing research limitations and provides insights into potential directions for future studies.

Key words: tooth bleaching material, advanced oxidation process, Fenton-like reaction, photocatalysis, piezoelectric catalysis

中图分类号: 

  • R781

《口腔癌、口咽癌——全生命周期诊疗及康复》出版发行"

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