国际口腔医学杂志 ›› 2026, Vol. 53 ›› Issue (3): 424-432.doi: 10.7518/gjkq.2026221

• 综述 • 上一篇    

正畸邻面去釉对牙体及牙周组织影响的研究进展

于晶晶1(),张欢欢1,刘馨蕾1,秦丹晨2,3,赵婷婷3,花放1,2,4()   

  1. 1.口颌系统重建与再生全国重点实验室;口腔生物医学教育部重点实验室;口腔医学湖北省重点实验室 武汉大学口腔医(学)院 武汉 430079
    2.武汉大学口腔医院循证口腔医学中心 武汉 430079
    3.武汉大学口腔医院口腔正畸一科 武汉 430079
    4.武汉大学口腔医院光谷院区正畸与儿童口腔中心 武汉 430223
  • 收稿日期:2024-12-30 修回日期:2025-07-10 出版日期:2026-05-01 发布日期:2026-04-24
  • 通讯作者: 花放
  • 作者简介:于晶晶,硕士,Email:jingjingyu@whu.edu.cn
  • 基金资助:
    国家自然科学基金(81901044);中国牙防基金会“爱笑少年”儿童青少年生长发育和口腔疾病防治项目(A2023-008)

Research progress in the impact of orthodontic interproximal enamel reduction on teeth and periodontium

Jingjing Yu1(),Huanhuan Zhang1,Xinlei Liu1,Danchen Qin2,3,Tingting Zhao3,Fang Hua1,2,4()   

  1. 1.State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
    2.Center for Evidence-Based Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
    3.Dept. of Orthodontics Division 1, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China
    4.Center for Orthodontics and Pediatric Dentistry at Optics Valley Branch, School & Hospital of Stomatology, Wuhan University, Wuhan 430223, China
  • Received:2024-12-30 Revised:2025-07-10 Online:2026-05-01 Published:2026-04-24
  • Contact: Fang Hua
  • Supported by:
    National Natural Science Foundation of China(81901044);China Oral Health Foundation Smile Teena-gers Research Fund(A2023-008)

摘要:

邻面去釉是正畸治疗中的一种常用临床操作,可用于存在轻中度牙列拥挤、牙齿形态不协调、前牙区黑三角、Bolton指数不调等的正畸患者。目前学界对于邻面去釉的安全性存在争议,关于其对牙体及牙周组织的影响尚缺乏共识。本文对近年来正畸邻面去釉对牙体及牙周组织影响的相关研究进行综述,以期为正畸医师制定相关临床决策及实施方案提供参考。

关键词: 邻面去釉, 牙面粗糙度, 釉质元素成分, 牙髓温度刺激, 牙周稳态, 龋易感性

Abstract:

Interproximal enamel reduction is a common clinical strategy in orthodontic treatment. It can be used for orthodontic patients with mild to moderate dentition crowding, tooth morphology incoordination, black triangle in ante-rior tooth areas, and Bolton index imbalance. At present, the safety of interproximal enamel reduction is controversial, and a consensus on its impact on teeth and periodontium is lacking. In this article, the recent research on the effect of interproximal enamel reduction on teeth and periodontium is reviewed to provide reference for orthodontists to make clinical decisions and implementation plans.

Key words: interproximal enamel reduction, surface enamel roughness, surface enamel composition, temperature rise in the pulp, periodontal homeostasis, susceptibility to dental caries

中图分类号: 

  • R783.5
[1] 余智爽, 邓怡. 无托槽隐形矫治器关闭邻面去釉间隙的生物力学研究[J]. 实用口腔医学杂志, 2020, 36(5): 775-778.
Yu ZS, Deng Y. Biomechanical study on closing the gap of interproximal enamel reduction by clear aligner[J]. J Pract Stomatol, 2020, 36(5): 775-778.
[2] 中华口腔医学会口腔正畸专业委员会. 口腔正畸无托槽隐形矫治技术指南(2021版)[J]. 中华口腔医学杂志, 2021, 56(10): 983-988.
Society of Orthodontics, Chinese Stomatological Association. Guidelines for clear aligner orthodontic treatment (2021)[J]. Chin J Stomatol, 2021, 56(10): 983-988.
[3] Dahhas FY, Almutairi NS, Almutairi RS, et al. The role of interproximal reduction (IPR) in clear aligner therapy: a critical analysis of indications, techniques, and outcomes[J]. Cureus, 2024, 16(3): e56644.
[4] 陈扬熙. 口腔正畸学——基础、技术与临床[M]. 北京: 人民卫生出版社, 2012.
Chen YX. Orthodontics: foundation, technology and clinical[M]. Beijing: People’s Medical Publishing House, 2012.
[5] 孟微, 鲁明星. 渗透树脂与多乐氟用于正畸邻面去釉后的疗效观察[J]. 世界最新医学信息文摘, 2020, 20(53): 153-154.
Meng W, Lu MX. Observation on the effect of ICON resin and duraphat on enamel demineralization after interproximal reduction[J]. World Latest Med Informat, 2020, 20(53): 153-154.
[6] 张婷, 鲍强. 用氟制剂和自酸蚀粘接剂预防邻面去釉并发症的临床效果分析[J]. 全科口腔医学电子杂志, 2020, 7(18): 4-6.
Zhang T, Bao Q. Analysis of the clinical effect of fluoride preparation and self etching adhesive in preventing the complications of adjacent enamel removal[J]. Electr J General Stomatol, 2020, 7(18): 4-6.
[7] Silvestrini Biavati F, Schiaffino V, Signore A, et al. Evaluation of enamel surfaces after different techniques of interproximal enamel reduction[J]. J Funct Biomater, 2023, 14(2): 110.
[8] 热克西. 不同邻面去釉方式对牙釉质粗糙度影响的体外研究[D]. 乌鲁木齐: 新疆医科大学, 2022.
Re KX. In vitro study on the effect of different IER methods on enamel roughness[D]. Urumqi: Xin-jiang Medical University, 2022.
[9] Poovattil KB, Sathyanarayana HP, Padmanabhan S. Does surface enamel composition and characteristics vary with inter proximal enamel reduction[J]. Clin Oral Investig, 2024, 28(3): 176.
[10] Butrus DJ, Chawshli OF. Evaluation of the enamel nano-topography influenced by different techniques of interproximal reduction: an atomic force microscopic study[J]. J Orthod, 2023, 50(2): 196-204.
[11] Katsigialou N, Sifakakis I, Zinelis S, et al. Manual and mechanical stripping-induced enamel roughness and elemental composition in vivo [J]. Eur J Orthod, 2023, 45(3): 250-257.
[12] Salvati E, Besnard C, Harper RA, et al. Finite element modelling and experimental validation of the enamel demineralisation process at the rod level[J]. J Adv Res, 2020, 29: 167-177.
[13] 于世凤. 口腔组织病理学[M]. 7版. 北京: 人民卫生出版社, 2012.
Yu SF. Oral histology and pathology[M]. 7th ed. Beijing: People’s Medical Publishing House, 2012.
[14] Harper RA, Shelton RM, James JD, et al. Acid-induced demineralisation of human enamel as a function of time and pH observed using X-ray and pola-rised light imaging[J]. Acta Biomater, 2021, 120: 240-248.
[15] Palomino L, Gonzalez-Gamboa I, Garcia-Mendoza M, et al. Grafting-from synthesis of plant-polynorbornene biohybrid materials[J]. ACS Macro Lett, 2024, 13(6): 726-733.
[16] Jiang Q, Yin Z, Yin H, et al. Study on triaxial compression performance and damage characteristics of fiber-reinforced ecological matrix cementing gangue gypsum fill material[J]. PLoS One, 2024, 19(5): e0299001.
[17] Chintokoma GC, Chebude Y, Kassahun SK. Cd2+ removal efficiency of activated carbon from Prosopis juliflora: optimization of preparation parameters by the Box-Behnken Design of Response Surface Me-thodology[J]. Heliyon, 2024, 10(10): e31357.
[18] Mutadza I, Ikiensikimama SS, Joel OF. Geo-mechanical and geo-morphology characterisation of the cap rocks in the Niger Delta for potential carbon capture and storage[J]. Heliyon, 2024, 10(10): e31206.
[19] Kelly AM, Kallistova A, Küchler EC, et al. Measu-ring the microscopic structures of human dental enamel can predict caries experience[J]. J Pers Med, 2020, 10(1): 5.
[20] Banga K, Arora N, Kannan S, et al. Evaluation of temperature rise in the pulp during various IPR techniques-an in vivo study[J]. Prog Orthod, 2020, 21(1): 40.
[21] Burke S, Burch JG, Tetz JA. Incidence and size of pretreatment overlap and posttreatment gingival embrasure space between maxillary central incisors[J]. Am J Orthod Dentofacial Orthop, 1994, 105(5): 506-511.
[22] Batra P, Daing A, Azam I, et al. Impact of altered gingival characteristics on smile esthetics: laypersons’ perspectives by Q sort methodology[J]. Am J Orthod Dentofacial Orthop, 2018, 154(1): 82-90.e2.
[23] Pugliese F, Hess R, Palomo L. Black triangles: preventing their occurrence, managing them when prevention is not practical[J]. Semin Orthod, 2019, 25(2): 175-186.
[24] Zhang Y, Wang X, Wang J, et al. IPR treatment and attachments design in clear aligner therapy and risk of open gingival embrasures in adults[J]. Prog Orthod, 2023, 24(1): 1.
[25] Nucci L, d’Apuzzo F, Nastri L, et al. Enamel interproximal reduction and periodontal health[J]. Semin Orthod, 2024, 30(2):146-149.
[26] Zachrisson BU, Nyøygaard L, Mobarak K. Dental health assessed more than 10 years after interproximal enamel reduction of mandibular anterior teeth[J]. Am J Orthod Dentofacial Orthop, 2007, 131(2): 162-169.
[27] Shalchi M, Abdollahi N, Shafiei Haghshenas E, et al. Effect of interdental enamel reduction on clinical attachment loss, bleeding on probing, and incidence of caries in treating class Ⅰ malocclusion cases: a retrospective cohort study[J]. Cureus, 2023, 15(2): e35018.
[28] Gómez-Aguirre JN, Argueta-Figueroa L, Castro-Gutiérrez MEM, et al. Effects of interproximal enamel reduction techniques used for orthodontics: a systematic review[J]. Orthod Craniofac Res, 2022, 25(3): 304-319.
[29] 孟焕新. 牙周病学[M]. 5版. 北京: 人民卫生出版社, 2020.
Meng HX. Periodontology[M]. 5th ed. Beijing: People’s Medical Publishing House, 2020.
[30] Sirri OR, Burhan AS, Hajeer MY, et al. Efficiency of corticision in accelerating leveling and alignment of crowded lower anterior teeth in young adult patients: a randomised controlled clinical trial[J]. J Clin Diagn Res, 2020, 14(10): ZC26-ZC31.
[31] Al-Ibrahim HM, Hajeer MY, Alkhouri I, et al. Leve-ling and alignment time and the periodontal status in patients with severe upper crowding treated by corticotomy-assisted self-ligating brackets in comparison with conventional or self-ligating brackets only: a 3-arm randomized controlled clinical trial[J]. J World Fed Orthod, 2022, 11(1): 3-11.
[32] Darwiche FH, Tashkandi NE, AlGhamdi M, et al. Effect of interproximal enamel reduction on interradicular bone volume in clear aligner therapy: a three-dimensional cone-beam computed tomography study[J]. Clin Oral Investig, 2024, 28(10): 552.
[33] 王松灵. 稳态医学在口腔医学中发展与应用的思考[J]. 中华口腔医学杂志, 2024, 59(2): 119-123.
Wang SL. Development and application of homeostatic medicine in stomatology[J]. Chin J Stomatol, 2024, 59(2): 119-123.
[34] 王志勇, 陈谦明. 牙周稳态维持与失衡中的区域免疫机制[J]. 中华口腔医学杂志, 2024, 59(2): 130-137.
Wang ZY, Chen QM. Regional immunity involved in the maintenance and imbalance of periodontal homeostasis[J]. Chin J Stomatol, 2024, 59(2): 130-137.
[35] Hathaway-Schrader JD, Novince CM. Maintaining homeostatic control of periodontal bone tissue[J]. Periodontol 2000, 2021, 86(1): 157-187.
[36] 曲红蕾, 陈发明. 非阻生第三磨牙与邻牙牙周稳态[J]. 中华口腔医学杂志, 2024, 59(2): 138-144.
Qu HL, Chen FM. Nonimpacted third molars and the periodontal homeostasis of their adjacent second molars[J]. Chin J Stomatol, 2024, 59(2): 138-144.
[37] 李政毅, 周学东, 彭显. 口腔微生物稳态调控与口腔疾病[J]. 中华口腔医学杂志, 2024, 59(2): 124-129.
Li ZY, Zhou XD, Peng X. Regulation of oral microbiota homeostasis and oral diseases[J]. Chin J Stomatol, 2024, 59(2): 124-129.
[38] Danesh G, PKKPodstawa, Schwartz CE, et al. Depth of acid penetration and enamel surface roughness associated with different methods of interproximal enamel reduction[J]. PLoS One, 2020, 15(3): e0229595.
[39] Koretsi V, Chatzigianni A, Sidiropoulou S. Enamel roughness and incidence of caries after interproximal enamel reduction: a systematic review[J]. Orthod Craniofac Res, 2014, 17(1): 1-13.
[40] Cremonini F, Giannoccaro V, Palone M, et al. In vitro study of tooth surfaces after interproximal ena-mel reduction: extraoral scanner and SEM analysis[J]. Pesqui Bras Odontopediatria Clín Integr, 2021, 21(supp1): e0021.
[41] Sugsompian K, Tansalarak R, Piyapattamin T. Comparison of the enamel surface roughness from diffe-rent polishing methods: scanning electron microscopy and atomic force microscopy investigation[J]. Eur J Dent, 2020, 14(2): 299-305.
[42] Harini R, Thulasiram D, Sabapathy K. Interproximal reduction in orthodontics-a review[J]. Europ J Mol Clin Med, 2020, 7(4): 1641-1644.
[43] De Felice ME, Nucci L, Fiori A, et al. Accuracy of interproximal enamel reduction during clear aligner treatment[J]. Prog Orthod, 2020, 21(1): 28.
[44] Almansouri N, Bakry AS, Abbassy MA, et al. Eva-luation of resin infiltration, fluoride and the biomime-tic mineralization of CPP-ACP in protecting enamel after orthodontic inter-proximal enamel reduction[J]. Biomimetics (Basel), 2023, 8(1): 82.
[45] 王凤欣. 在邻面去釉后应用自酸蚀粘结剂的防龋效果研究[J]. 黑龙江医药, 2020, 3(2): 422-424.
Wang FX. Study on the anti-caries effect of self-etch binder after interproximal enamel reduction[J]. Heilongjiang Med J, 2020, 3(2): 422-424.
[46] 赵萌. 正畸牙邻面去釉后不同试剂处理对牙釉质再矿化的影响[D]. 唐山: 华北理工大学, 2020.
Zhao M. Effects of different reagent treatments on enamel remineralization after orthodontic tooth interproximal enamel reduction[D]. Tangshan: North China University of Science and Technology, 2020.
[47] 胡蓓蓓, 李雪微, 白海, 等. 新型纳米HAP复合改性材料制备及其防龋性能研究[J]. 实用口腔医学杂志, 2020, 36(1): 86-90.
Hu BB, Li XW, Bai H, et al. Preparation and anti-caries properties of novel nano-hydroxyapetite mo-dified composites[J]. J Pract Stomatol, 2020, 36(1): 86-90.
[48] 曲珊琳, 于烁, 马晓琳, 等. pH响应型抗菌纳米材料在抑制口腔菌斑生物膜领域的研究进展[J]. 中华口腔医学杂志, 2023, 58(3): 292-297.
Qu SL, Yu S, Ma XL, et al. Research progress in pH‑responsive antibacterial nanomaterials for inhi-biting oral plaque biofilms[J]. Chin J Stomatol, 2023, 58(3): 292-297.
[49] 全璐璐. 生物活性玻璃溶液对邻面去釉后的再矿化研究[D]. 唐山: 华北理工大学, 2021.
Quan LL. The effect of remineralization on BAG solution after interproximal enamel reduction[D]. Tangshan: North China University of Science and Technology, 2021.
[50] Vicente A, Ortiz-Ruiz AJ, González-Paz BM, et al. Effectiveness of a toothpaste and a serum contai-ning calcium silicate on protecting the enamel after interproximal reduction against demineralization[J]. Sci Rep, 2021, 11(1): 834.
[51] Vaid NR, Adel SM. Contemporary orthodontic workflows: a panacea for efficiency[J]. Semin Orthod, 2023, 29(1): 1-3.
[52] Zanatta RF, Caneppele TMF, Scaramucci T, et al. Protective effect of fluorides on erosion and erosion/abrasion in enamel: a systematic review and meta-analysis of randomized in situ trials[J]. Arch Oral Biol, 2020, 120: 104945.
[53] Perdigão J. Resin infiltration of enamel white spot lesions: an ultramorphological analysis[J]. J Esthet Restor Dent, 2020, 32(3): 317-324.
[54] Reise M, Kranz S, Heyder M, et al. Effectiveness of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) compared to fluoride products in an in-vitro demineralization model[J]. Materials (Basel), 2021, 14(20): 5974.
[55] Ploumis EJ. Changing times, changing paradigms: emerging trends in orthodontic practice opportunities[J]. Semin Orthod, 2022, 28(1):1-4.
[56] Ozturk T, Yagci A. Association between incisor positions and amount of interdental stripping in patients undergoing orthodontic treatment[J]. Am J Orthod Dentofacial Orthop, 2021, 159(6): e439-e448.
[57] Abasseri T, Weir T, Meade MJ. Interproximal reduction in the refinement phase of Invisalign treatment: a quantitative analysis[J]. Am J Orthod Dentofacial Orthop, 2024, 165(6): 689-696.
[58] Yagci F, Turker G, Yilanci H. Determination of the thickness of the safe enamel for laminate veneer preparation and orthodontic stripping by CBCT[J]. Niger J Clin Pract, 2021, 24(4): 525-533.
[59] Kailasam V, Rangarajan H, Easwaran HN, et al. Proximal enamel thickness of the permanent teeth: a systematic review and meta-analysis[J]. Am J Orthod Dentofacial Orthop, 2021, 160(6): 793-804.e3.
[60] 热克西, 古力巴哈·买买提力. 邻面去釉技术及其临床应用的研究进展[J]. 中国美容医学, 2022, 31(10): 202-205.
Re KX, Gulibaha·Maimaitil. Research progress of adjacent surface deglazing technology and clinical application[J]. Chin J Aesth Med, 2022, 31(10): 202-205.
[61] Güleç Ergün P, Arman Özçırpıcı A, Atakan Kocabalkan A, et al. Evaluation of the consistency of two interproximal reduction methods in clear aligner therapy: a preliminary study[J]. Turk J Orthod, 2024, 37(1): 1-6.
[62] Kalemaj Z, Levrini L. Quantitative evaluation of implemented interproximal enamel reduction during aligner therapy[J]. Angle Orthod, 2021, 91(1): 61-66.
[63] Serbanoiu DC, Vartolomei AC, Ghiga DV, et al. Comparative evaluation of dental enamel microhardness following various methods of interproximal reduction: a vickers hardness tester investigation[J]. Biomedicines, 2024, 12(5): 1132.
[64] Serbanoiu DC, Vartolomei AC, Ghiga DV, et al. A comparative analysis of enamel surface roughness following various interproximal reduction techniques: an examination using scanning electron microscopy and atomic force microscopy[J]. Biomedicines, 2024, 12(8): 1629.
[65] Laganà G, Malara A, Lione R, et al. Enamel interproximal reduction during treatment with clear aligners: digital planning versus OrthoCAD analysis[J]. BMC Oral Health, 2021, 21(1): 199.
[66] Hariharan A, Arqub SA, Gandhi V, et al. Evaluation of interproximal reduction in individual teeth, and full arch assessment in clear aligner therapy: digital planning versus 3D model analysis after reduction[J]. Prog Orthod, 2022, 23(1): 9.
[67] Triduo M, Zubizarreta-Macho Á, Pérez-Barquero JA, et al. A novel digital technique to quantify the area and volume of enamel removal after interproximal enamel reduction[J]. Appl Sci, 2021, 11(3): 1274.
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[2] 徐莉. 菌斑液与龋易感性关系的研究近况[J]. 国际口腔医学杂志, 2004, 31(S1): -.
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