国际口腔医学杂志 ›› 2019, Vol. 46 ›› Issue (3): 258-262.doi: 10.7518/gjkq.2019033
Xiaomeng Wang1,Xiao Wang1,Ce Shi2,3,Hongchen Sun2,3,Yang Huang1()
摘要:
下颌骨是颅面部唯一能自主活动的骨,可发挥咀嚼、发音和吞咽等多种重要功能。骨形态发生蛋白(BMP)信号通路在骨和软骨的形成及稳态维持中起到重要作用,对下颌骨的发育是不可或缺的。已知BMP信号通路的配体、受体及其下游多种细胞因子与其他信号通路相关联,组成一个复杂且庞大的信号网络,共同调节下颌骨的发育。本文主要介绍BMP信号通路以及与BMP信号通路交叉对话的信号通路在下颌骨发育中的作用。
中图分类号:
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