Int J Stomatol

Int J Stomatol ›› 2023, Vol. 50 ›› Issue (3): 335-340.doi: 10.7518/gjkq.2023059

• Reviews • Previous Articles     Next Articles

Research progress on dual-energy CT in the evaluation of cervical lymph node disease

Yan Zening1(),Sun Rui1,2(),Li Fei1,Zhang Jiansen1   

  1. 1.School and Hospital of Stomatology, Shanxi Medical University, Taiyuan 030012, China
    2.Dept. of Stomatology, Shanxi Bethune Hospital (Tongji Shanxi Hospital), Taiyuan 030032, China
  • Received:2022-09-15 Revised:2023-01-16 Online:2023-05-01 Published:2023-05-16
  • Contact: Rui Sun E-mail:776219211@qq.com;ruidoctor@163.com
  • Supported by:
    Natural Science Foundation of Shanxi Province(202103021224378)

RichHTML

30

PDF (PC)

176

Abstract:

Early detection and qualitative diagnosis of head and neck lymphadenopathy is very important, which is helpful for timely clinical intervention and treatment plan formulation, delaying or stopping disease progression. At pre-sent, multiple sets of dual-energy CT images, such as virtual non-contrast image, iodine map, virtual monoenergetic ima-ges, spectral Hounsfield unit attenuation curves and blended images have been gradually used to evaluate the head and neck lymph node lesions, providing many quantitative indicators for the qualitative, staging and pathological classification of lymph node lesions. This article reviews the research progress of multi-group post-processing images and related parameters of dual-energy CT in the evaluation of cervical lymph node diseases.

Key words: cervical lymph node, cervical lymph node enlargement, dual-energy CT, head and neck imaging

CLC Number: 

  • R 782.05+1

TrendMD: 
1 Prativadi R, Dahiya N, Kamaya A, et al. Chapter 5 ultrasound characteristics of benign vs malignant cervical lymph nodes[J]. Semin Ultrasound CT MR, 2017, 38(5): 506-515.
2 Kim JH, Choi KY, Lee SH, et al. The value of CT, MRI, and PET-CT in detecting retropharyngeal lymph node metastasis of head and neck squamous cell carcinoma[J]. BMC Med Imaging, 2020, 20(1): 88.
3 Bae MR, Roh JL, Kim JS, et al. 18F-FDG PET/CT versus CT/MR imaging for detection of neck lymph node metastasis in palpably node-negative oral cavity cancer[J]. J Cancer Res Clin Oncol, 2020, 146(1): 237-244.
4 Linz C, Brands RC, Herterich T, et al. Accuracy of 18-F fluorodeoxyglucose positron emission tomographic/computed tomographic imaging in primary staging of squamous cell carcinoma of the oral cavity[J]. JAMA Netw Open, 2021, 4(4): e217083.
5 Strohl MP, Ha PK, Flavell RR, et al. PET/CT in surgical planning for head and neck cancer[J]. Semin Nucl Med, 2021, 51(1): 50-58.
6 Liao LJ, Lo WC, Hsu WL, et al. Detection of cervical lymph node metastasis in head and neck cancer patients with clinically N0 neck-a meta-analysis comparing different imaging modalities[J]. BMC Cancer, 2012, 12: 236.
7 Parakh A, Macri F, Sahani D. Dual-energy compu-ted tomography: dose reduction, series reduction, and contrast load reduction in dual-energy compu-ted tomography[J]. Radiol Clin North Am, 2018, 56(4): 601-624.
8 Martin SS, Czwikla R, Wichmann JL, et al. Dual-energy CT-based iodine quantification to differentiate abdominal malignant lymphoma from lymph node metastasis[J]. Eur J Radiol, 2018, 105: 255-260.
9 Zeng YR, Yang QH, Liu QY, et al. Dual energy computed tomography for detection of metastatic lymph nodes in patients with hepatocellular carcinoma[J]. World J Gastroenterol, 2019, 25(16): 1986-1996.
10 An C, Li DY, Li S, et al. Deep learning radiomics of dual-energy computed tomography for predicting lymph node metastases of pancreatic ductal adenocarcinoma[J]. Eur J Nucl Med Mol Imaging, 2022, 49(4): 1187-1199.
11 Eisenmenger LB, Wiggins RH 3rd. Imaging of head and neck lymph nodes[J]. Radiol Clin North Am, 2015, 53(1): 115-132.
12 Saindane AM. Pitfalls in the staging of cervical lymph node metastasis[J]. Neuroimaging Clin N Am, 2013, 23(1): 147-166.
13 Swensen SJ, Brown LR, Colby TV, et al. Pulmonary nodules: CT evaluation of enhancement with iodi-nated contrast material[J]. Radiology, 1995, 194(2): 393-398.
14 Chae EJ, Song JW, Krauss B, et al. Dual-energy computed tomography characterization of solitary pulmonary nodules[J]. J Thorac Imaging, 2010, 25(4): 301-310.
15 Fu F, He AW, Zhang Y, et al. Dua-energy virtual noncontrast imaging in diagnosis of cervical metastasis lymph nodes[J]. J Cancer Res Ther, 2015, 11(): C202-C204.
16 Yang YY, Jia XX, Deng YM, et al. Can virtual non-enhanced CT be used to replace true non-enhanced CT for the detection of palpable cervical lymph nodes? A preliminary study[J]. Jpn J Radiol, 2014, 32(6): 324-330.
17 石梦昀, 杨斌, 边莉, 等. CT双能量虚拟平扫在颈部肿大淋巴结的诊断价值[J]. 中国医学影像学杂志, 2013, 21(11): 812-815.
Shi MY, Yang B, Bian L, et al. Application of dual-energy virtual non-contrast imaging in evaluating enlarged cervical lymph nodes[J]. Chin J Med Ima-ging, 2013, 21(11): 812-815.
18 Chandarana H, Megibow AJ, Cohen BA, et al. Iodine quantification with dual-energy CT: phantom study and preliminary experience with renal masses[J]. AJR Am J Roentgenol, 2011, 196(6): W693-W700.
19 Tawfik AM, Razek AA, Kerl JM, et al. Comparison of dual-energy CT-derived iodine content and iodine overlay of normal, inflammatory and metastatic squamous cell carcinoma cervical lymph nodes[J]. Eur Radiol, 2014, 24(3): 574-580.
20 Zenk J, Bozzato A, Steinhart H, et al. Metastatic and inflammatory cervical lymph nodes as analyzed by contrast-enhanced color-coded Doppler ultrasono-graphy: quantitative dynamic perfusion patterns and histopathologic correlation[J]. Ann Otol Rhinol Laryngol, 2005, 114(1 Pt 1): 43-47.
21 He MZ, Lin CL, Yin L, et al. Value of dual-energy computed tomography for diagnosing cervical lymph node metastasis in patients with papillary thyroid cancer[J]. J Comput Assist Tomogr, 2019, 43(6): 970-975.
22 Zou Y, Zheng MZ, Qi ZY, et al. Dual-energy computed tomography could reliably differentiate metastatic from non-metastatic lymph nodes of less than 0.5 cm in patients with papillary thyroid carcinoma[J]. Quant Imaging Med Surg, 2021, 11(4): 1354-1367.
23 Liang H, Li AY, Li YF, et al. A retrospective study of dual-energy CT for clinical detecting of metasta-tic cervical lymph nodes in laryngeal and hypo-pharyngeal squamous cell carcinoma[J]. Acta Otolaryngol, 2015, 135(7): 722-728.
24 Bahig H, Lapointe A, Bedwani S, et al. Dual-energy computed tomography for prediction of loco-regio-nal recurrence after radiotherapy in larynx and hypopharynx squamous cell carcinoma[J]. Eur J Radiol, 2019, 110: 1-6.
25 Goo HW. Dual-energy lung perfusion and ventilation CT in children[J]. Pediatr Radiol, 2013, 43(3): 298-307.
26 Siegel MJ, Curtis WA, Ramirez-Giraldo JC. Effects of dual-energy technique on radiation exposure and image quality in pediatric body CT[J]. AJR Am J Roentgenol, 2016, 207(4): 826-835.
27 Siegel MJ, Ramirez-Giraldo JC. Dual-energy CT in children: imaging algorithms and clinical applications[J]. Radiology, 2019, 291(2): 286-297.
28 Nair JR, DeBlois F, Ong T, et al. Dual-energy CT: balance between iodine attenuation and artifact reduction for the evaluation of head and neck cancer[J]. J Comput Assist Tomogr, 2017, 41(6): 931-936.
29 Wichmann JL, Nöske EM, Kraft J, et al. Virtual monoenergetic dual-energy computed tomography: optimization of kiloelectron volt settings in head and neck cancer[J]. Invest Radiol, 2014, 49(11): 735-741.
30 Lam S, Gupta R, Levental M, et al. Optimal virtual monochromatic images for evaluation of normal tissues and head and neck cancer using dual-energy CT[J]. AJNR Am J Neuroradiol, 2015, 36(8): 1518-1524.
31 Seidler M, Forghani B, Reinhold C, et al. Dual-energy CT texture analysis with machine learning for the evaluation and characterization of cervical lymphadenopathy[J]. Comput Struct Biotechnol J, 2019, 17: 1009-1015.
32 Forghani R, De Man B, Gupta R. Dual-energy computed tomography: physical principles, approaches to scanning, usage, and implementation: part 2[J]. Neuroimaging Clin N Am, 2017, 27(3): 385-400.
33 Forghani R, Srinivasan A, Forghani B. Advanced tissue characterization and texture analysis using dual-energy computed tomography: horizons and emer-ging applications[J]. Neuroimaging Clin N Am, 2017, 27(3): 533-546.
34 Forghani R, Levental M, Gupta R, et al. Different spectral Hounsfield unit curve and high-energy virtual monochromatic image characteristics of squamous cell carcinoma compared with nonossified thyroid cartilage[J]. AJNR Am J Neuroradiol, 2015, 36(6): 1194-1200.
35 Srinivasan A, Parker RA, Manjunathan A, et al. Differentiation of benign and malignant neck pathologies: preliminary experience using spectral compu-ted tomography[J]. J Comput Assist Tomogr, 2013, 37(5): 666-672.
36 Liang H, Li AY, Li YF, et al. A retrospective study of dual-energy CT for clinical detecting of metasta-tic cervical lymph nodes in laryngeal and hypopharyngeal squamous cell carcinoma[J]. Acta Otolaryngol, 2015, 135(7): 722-728.
37 Liu XW, Ouyang D, Li H, et al. Papillary thyroid cancer: dual-energy spectral CT quantitative para-meters for preoperative diagnosis of metastasis to the cervical lymph nodes[J]. Radiology, 2015, 275(1): 167-176.
38 Vogl TJ, Schulz B, Bauer RW, et al. Dual-energy CT applications in head and neck imaging[J]. AJR Am J Roentgenol, 2012, 199(5 ): S34-S39.
39 Tawfik AM, Kerl JM, Razek AA, et al. Image quality and radiation dose of dual-energy CT of the head and neck compared with a standard 120-kVp acquisition[J]. AJNR Am J Neuroradiol, 2011, 32(11): 1994-1999.
40 Tawfik AM, Kerl JM, Bauer RW, et al. Dual-energy CT of head and neck cancer: average weighting of low-and high-voltage acquisitions to improve lesion delineation and image quality-initial clinical expe-rience[J]. Invest Radiol, 2012, 47(5): 306-311.
41 Scholtz JE, Hüsers K, Kaup M, et al. Non-linear image blending improves visualization of head and neck primary squamous cell carcinoma compared to linear blending in dual-energy CT[J]. Clin Radiol, 2015, 70(2): 168-175.
42 Yang FF, Dong J, Wang XT, et al. Non-small cell lung cancer: spectral computed tomography quantitative parameters for preoperative diagnosis of metastatic lymph nodes[J]. Eur J Radiol, 2017, 89: 129-135.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[7] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[8] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[9] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[10] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .