Int J Stomatol

Inter J Stomatol ›› 2015, Vol. 42 ›› Issue (1): 106-110.doi: 10.7518/gjkq.2015.01.026

Previous Articles     Next Articles

The nitric oxide of nonenzymatic pathway and its role in ischemia-reperfusion injury of free skin flap

Ouyang Jiajie, Niu Qifang, Han Zhengxue   

  1. Dept. of Oral and Maxillofacial Surgery, Beijing Stomatological Hospital of Capital Medical University, Beijing 100050, China
  • Online:2015-01-01 Published:2015-01-01

RichHTML

3

PDF (PC)

541

Abstract:

Nitric oxide(NO) relaxes thevascular smooth muscle of blood vessels, increases blood flow perfusion, and protects tissues from ischemia-reperfusion injury(IRI). Hypoxic and low pH conditions favor the production of NO fromnonenzymatic pathways to protect the flap tissue from IRI. This article focuses on the relationship between IRI of free skin flap and nitric oxide and presents the latest research on nonenzymatic NO-producing pathways and their role in the IRI of the free skin flap. This paper also investigates the value of these pathwaysin preventing IRI in flaps and provides the oretical bases and new ideas preventing and treating IRI.

Key words: nitric oxide, free skin flap, ischemia-reperfusion injury


TrendMD: 
[1] Wang Yanzhi, Li Shu.. Nitric oxide and other gas signaling molecules and periodontal disease [J]. Inter J Stomatol, 2014, 41(2): 204-208.
[2] HOU Hai-juan1, ZHANG Jie1, HUANG Ping2.. Research progress on nitric oxide synthase gene polymorphisms on systemic diseases and periodontitis [J]. Inter J Stomatol, 2011, 38(2): 200-203.
[3] XU Xu-jie, WU Li-ping. The influence of L-arginine and NG-nitro-L-arginine methyl ester synthase express [J]. Inter J Stomatol, 2009, 36(4): 379-382.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[2] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[3] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[4] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[5] . [J]. Foreign Med Sci: Stomatol, 1999, 26(06): .
[6] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[7] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[8] . [J]. Foreign Med Sci: Stomatol, 1999, 26(05): .
[9] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .
[10] . [J]. Foreign Med Sci: Stomatol, 1999, 26(04): .