Int J Stomatol

Inter J Stomatol ›› 2011, Vol. 38 ›› Issue (5): 578-580.doi: 10.3969/j.issn.1673-5749.2011.05.022

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Research progress on inhibitor of DNA binding -1 and carcinogenesis

Ye Mingfu1, Zheng Youhua2.   

  1. 1. Dept. of Oral and Maxillofacial Surgery, Xiamen Stomatological Hospital, Xiamen 361003, China; 2. Dept. of Oral and Maxillofacial Surgery, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou 510055, China
  • Received:2010-08-04 Revised:2011-05-27 Online:2011-09-20 Published:2011-09-20

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Abstract:

Inhibitor of DNA binding（Id）-1 has been identified for nearly 20 years, and it involved in the carcinogenesis of a variety of cancer as an oncogene. This review was focused on Id-1, which included its carcinogenic and effect on angiogenesis, invasion and migration of neoplasms, as well as the potential mechanism of Id-1 in drug resistance of cancer cells.

Key words: inhibitor of DNA binding-1, oncogene, carcinogenesis


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