Int J Stomatol

Inter J Stomatol

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The relationship between growth differentiation factor-15 and neoplasms

ZHANG Lei, ZHONG Lai-ping, ZHANG Zhi-yuan   

  1. Dept. of Oral and Maxillofacial Surgery, The Ninth People′s Hospital, School of
  • Received:2008-07-09 Revised:2008-11-25 Online:2009-03-20 Published:2009-03-20
  • Contact: ZHANG Zhi-yuan

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Abstract: Growth differentiation factor-15（GDF-15） is a member of the transforming growth factor-β（TGF-β）superfamily, involved in the physiological or pathological progression of tissue differentiation, inflammation, trauma
and neoplasms. This article reviewed the structure of GDF-15, the relationship between GDF-15 expression and neoplasms development and progression, and the regulation of GDF-15 expression.


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