Abstract: Objective To assess the clinical features and the treatment results of glossal adenoid cystic carcinoma（ACC）. Methods A retrospective analysis was performed on 25 patients with ACC of the tongue by their clinical manifestation, the therapy and follow-up information. Results There were 20 patients of operation, and 5 patients refused it and lost of following-up. The patients of operation were followed up from 2 to 24 years. The overall 3, 5, 10 and 15-year survival rate of patients was 78.95%, 58.82%, 28.57%, 10.00%, respectively. Conclusion Glossal ACC, especially the body of tongue, is not easy to exact diagnosis in early stage. It progresses slowly and also has the tendency of recurrence and cancerous metastasis. Thus it is necessary to do thorough surgery.