Int J Stomatol

Inter J Stomatol ›› 2010, Vol. 37 ›› Issue (6): 695-698.doi: 10.3969/j.issn.1673-5749.2010.06.021

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The role of Th17 cell in Sj魻gren’s syndrome pathogenesis

LIU Hao, JIANG Guang-shui.   

  1. （Dept. of Oral Medicine, School of Stomatology, Shandong University, Jinan 250012, China; Shandong Provincial Key Laboratory of Oral Biomedicine, Jinan 250012, China）
  • Online:2010-11-20 Published:2010-11-20

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Abstract:

It has been characterized that Th17 cell and its related cytokines, such as IL-17, IL-6, IL-23 and IL-21, play important roles in anti-inflammatory and autoimmune diseases. They also are involved in the pathogenesis of Sj觟gren’s syndrome. The article summarized the current information on the functions of Th17 cell and its related cytokines, and the role of them in Sj觟gren’s syndrome pathogenesis.

Key words: Sj觟gren&rsquo, s syndrome； cytokines； autoimmunity


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