国际口腔医学杂志 ›› 2017, Vol. 44 ›› Issue (6): 707-711.doi: 10.7518/gjkq.2017.06.016

• 综述 • 上一篇    下一篇

A型肉毒杆菌毒素在口腔颌面部的临床应用

佘杨杨, 农晓琳   

  1. 广西医科大学口腔医学院•附属口腔医院口腔颌面外科 南宁 530021
  • 收稿日期:2017-02-06 修回日期:2017-05-03 出版日期:2017-11-01 发布日期:2017-11-01
  • 通讯作者: 农晓琳,教授,博士,Email:xnong@gxmu.edu.cn
  • 作者简介:佘杨杨,硕士,Email:sheyangyang7@163.com
  • 基金资助:
    广西科学研究与技术开发计划课题(桂科能14123006-2); 广西研究生教育创新计划项目(201010598RY10)

Clinical application of botulinum toxin type A in oral and maxillofacial region

She Yangyang, Nong Xiaolin.   

  1. Dept. of Oral and Maxillofacial Surgery, College and Hospital of Stomatology, Guangxi Medical University, Nanning 530021, China
  • Received:2017-02-06 Revised:2017-05-03 Online:2017-11-01 Published:2017-11-01
  • Supported by:
    This study was supported by Scientific Research and Technology Development Project of Guangxi(14123006-2) and Innovation Project of Guangxi Graduate Education(201010598RY10).

摘要: A型肉毒杆菌毒素(BTX-A)是肉毒杆菌产生的一种细菌外毒素,通过抑制神经-肌肉接头处乙酰胆碱的释放而发挥作用。近年来研究发现,BTX-A可应用于口腔颌面部整形美容及一些口腔疾病的治疗,为口腔疾病替代治疗提供了新方法和新方向。本文综述了BTX-A的作用机制、在口腔颌面部的临床应用、禁忌证、操作注意事项、并发症及治疗。

关键词: A型肉毒杆菌毒素, 口腔颌面部, 临床应用

Abstract: Botulinum toxin type A(BTX-A) is a kind of exotoxin produced by the bacterium Clostridium botulinum which works by inhibiting the release of acetylcholine at the neuromuscular junction. Recent studies have found that BTX-A can be used in the oral and maxillofacial plastic surgery and the treatment of some oral diseases, providing a new method and a new direction for alternative treatment of oral diseases. The present review focuses on the mechanism, clinical application in the oral and maxillofacial region, operation cautions, contraindications and treatment of BTX-A.

Key words: botulinum toxin type A, oral and maxillofacial region, clinical application

中图分类号: 

  • R782
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