动物试验,纳米羟磷灰石/聚酰胺-66,牙种植体," /> 动物试验,纳米羟磷灰石/聚酰胺-66,牙种植体,"/> animal experiment, nano-hydroxyapatite/polyamide-66,
dental implant,"/> Animal experimental study of nano-hydroxyapatite/polyamide-66 dental implantation
Int J Stomatol

Inter J Stomatol ›› 2010, Vol. 37 ›› Issue (6): 629-633.doi: 10.3969/j.issn.1673-5749.2010.06.003

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Animal experimental study of nano-hydroxyapatite/polyamide-66 dental implantation

LI Wan-shan1, DAI Jing-bo2, ZHONG Yu-xiang1, LIANG Li1, LIAO Li-shu1, LI Yuan-gui1, WEI Shi-cheng3.   

  1. 1. Dept. of Stomatology, Children’s Hospital of
    Chongqing Medical University, Chongqing 400014, China; 2. Daping Stomatological
    Clinic, Bayi Dental Department of Chongqing, Chongqing 400020, China; 3. Dept.
    of Oral and Maxillofacial Surgery, School of Stomatology, Peking University,
    Beijing 100081, China
  • Online:2010-11-20 Published:2010-11-20

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Abstract:

Objective
 The aim of this study was to evaluate
the clinical applicability of the dental implant made of
nano-hydroxyapatite/polyamide-66（nHA/PA-66） composite according to the animal experiment. Methods  13 implants, which were made of nHA/PA-66
composite, were randomly implanted into the fresh tooth extraction wound in the
anterior teeth region of five adult mongrel dogs. The five dogs were sacrificed
singly at 4, 8, 12, 16 and 20 weeks postoperatively. Histological and
radiographical analyses were performed after the animals were sacrificed. Results  In addition to one implant fallen off after 8
weeks, the rest of the 12 plants existed well. X ray examination, the gaps
between the implant and alveolar bone were no significant broadening or
narrowing. Hematoxylin-eosin staining histological examination, there were
connective tissues formed in the gaps. We also found that its quantity
gradually increased and its orientating changed over time. Conclusion  The study
confirmed that the connective tissues formed in the gaps between the implant
and alveolar bone. We wonder that the connective tissues came from healthy
periodontium of alveolar fossa or fiber wrapping surrounding the implants. The
further study should be continued.

Key words: animal experiment')">animal experiment, nano-hydroxyapatite/polyamide-66')"> nano-hydroxyapatite/polyamide-66,
dental implant')">
dental implant


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