Abstract: Objective To investigate the effects of matrine on inhibition of cell proliferating in human adenoid cystic carcinoma cell line ACC-M. Methods ACC-M was cultured in vitro by different concentration matrine. Inhibitory effect of proliferation was investigate in light microscope, by the way of MTT and flow cytometry analysis.
Results Proliferation of ACC-M cells was inhibited obviously and cell cycle was arrested by treatment of matrine. Conclusion Matrine could obviously inhibit the proliferation of ACC-M cells. One of mechanisms could be cell cycle arrested for inhibition of cell proliferation.