Int J Stomatol

Int J Stomatol ›› 2022, Vol. 49 ›› Issue (3): 328-331.doi: 10.7518/gjkq.2022046

• Case Report • Previous Articles     Next Articles

Pleomorphic adenoma with extensive keratin cysts: a case report

Zhai Xiaojing1(),Cao Shi2,Xin Wenlong3,Cao Shan1,Zhang Hao3()   

  1. 1.The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China
    2.Dept. of Pathology, The First Hospital of Lanzhou University, Lanzhou 730000, China
    3.Dept. of Radiology, The First Hospital of Lanzhou University, Lanzhou 730000, China
  • Received:2021-08-03 Revised:2022-01-08 Online:2022-05-01 Published:2022-05-09
  • Contact: Hao Zhang E-mail:691439893@qq.com;zhanghao@lzu.edu.cn

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Abstract:

Pleomorphic adenoma, which has a diverse histology, is the most common benign tumor in the salivary glands. About 25% of pleomorphic adenoma is associated with squamous metaplasia, while cases with extensive squamous metaplasia and keratin cysts are unusual. Thus, there is a need to differentiate this from other cystic lesions, squamous cell carcinoma, mucoepidermoid carcinoma. In this work, we reported a case characterized by extensive keratin cyst formations. Squamous metaplasia and keratin cyst components account for about 40% of pleomorphic adenomas. Finally, through a literature review, we summarized the clinicopathological features, imaging examinations, differential diagnoses, treatments, and prognosis of pleomorphic adenoma with extensive keratin cysts.

Key words: pleomorphic adenoma, pleomorphic adenoma with extensive keratin cyst, pleomorphic adenoma with squamous metaplasia

CLC Number: 

  • R 739.87

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Fig 1

Pleomorphic adenoma with extensive keratin cysts"

Tab　1

Clinical features of pleomorphic adenoma with keratin cysts in the literatures"

参考文献年龄/岁性别部位病程临床表现大小/mm治疗随访
[3]50女硬腭1周硬腭后外侧肿胀50×50×15手术不详
[4]16女右侧腮腺浅叶1~2年缓慢生长的肿块20×20手术9个月未复发
[5]52男上腭1年上腭肿胀15×13×13手术不详
[6]16女右侧脸颊部3年右脸颊肿胀15×15手术不详
[7]26男右侧腮腺3年坚固、无痛、活动缓慢的肿块30×25×25手术不详
[8]50男下颌下腺6个月颌下肿胀50×30手术不详
[9]37男口腔前庭10年无痛性肿块20手术不详
[10]62男硬腭3~4个月无痛性肿块25×15×8手术不详
[11]21男左侧下颌下腺6个月肿块62×75手术不详
[12]54男右侧腮腺浅叶20年右侧腮腺区疼痛肿胀1月余17×12×12手术18个月未复发
[13]28男眶内颊部6年肿块20×20×15手术不详
[14]28男上腭7~8年缓慢生长的无痛肿块10×10手术不详
[15]37男左侧腮腺浅叶2年缓慢生长的无痛肿块20×20手术不详
[16]36男右侧腮腺4年缓慢生长的无痛肿块70×130×70手术7年未复发
本例32男右侧腮腺2年缓慢生长的肿块40×25×20手术6个月未复发
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[1] Yu Dongyang,Li Shaodong,Han Lei,Shan Ben,Liu Yong,Zhao Zhengyu. Differentiation of pleomorphic adenoma and adenolymphoma of parotid gland by CT morphological features, gender and radiomics [J]. Int J Stomatol, 2023, 50(5): 506-513.
[2] Xia Feifei,Qin Wenjuan,Feng Jia,Zhou Xuyang,Sun Ercan,Li Changxue. Value research on differential diagnosis of pleomorphic adenomas and adenolymphoma by histogram analysis of ultrasound gray [J]. Int J Stomatol, 2022, 49(1): 60-65.
[3] Li Tian, Sun Guowen, Tang Enyi.. Research progress on carcinoma ex-pleomorphic adenoma [J]. Inter J Stomatol, 2013, 40(5): 642-644.
[4] HU Yu- hua, LI Jiang.. Advances in the study of mechanisms of malignant tr ansformation of salivary pleomorphic adenoma [J]. Inter J Stomatol, 2007, 34(06): 449-451.
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