Int J Stomatol ›› 2019, Vol. 46 ›› Issue (3): 249-252.doi: 10.7518/gjkq.2019047

• Expert Forum •     Next Articles

Research on oral metabonomics

Wei Li(),Jinglin Zhou   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & West China School of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2019-01-28 Revised:2019-03-16 Online:2019-05-01 Published:2019-06-05
  • Contact: Wei Li E-mail:leewei2000@sina.com
  • Supported by:
    This study was supported by Major Scientific and Technological Research Projects of the Ministry of Education(307022);The Grant of Scientific and Technological Plan in Sichuan Province(2014SZ0050);Research Fund for Excellent Young Scholars of Sichuan University(2009SCU11162)

Abstract:

Metabonomics, as a part of system biology, is an approach to study the metabolism of diverse organisms, elucidate biological processes and find characteristic biomarkers of physiological states. As two key technologies, nuclear magnetic resonance (NMR) or mass spectra (MS) is used to detect the biological fluids, combined with the chemometrics method draw the metabolic pathway map and characteristic metabolites. It is widely used to detecting disease classification, drug toxicity assessment, plant classification, and detecting marine environment and food safety. This review demonstrates the methods, result, conclusions and research progress of metabonomics in stomatology.

Key words: metabonomics, nuclear magnetic resonance, mass spectra, oral disease

CLC Number: 

  • Q591

TrendMD: 
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