Int J Stomatol

Inter J Stomatol ›› 2015, Vol. 42 ›› Issue (2): 177-180.doi: 10.7518/gjkq.2015.02.014

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Prevention and treatment of radiation- and chemotherapy-induced oral mucositis

Lü Danni1, Li Ronglin1, Yang Guangwei2, Li Chunyang3   

  1. 1. Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China; 2. Dept. of Radiotherapy, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China; 3. Dept. of Stomatology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, China
  • Received:2014-04-10 Revised:2014-08-12 Online:2015-03-01 Published:2015-03-01

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Abstract:

Oral mucositis(OM), a common cytotoxic complication in the treatment of head and neck cancers, is a limiting factor for radiotherapy or chemotherapy. By impairing oral function, OM can result in severe pain, affect the intake of nutrition and increase the risk for infections. It may also postpone anti-cancer plans. Reduction strategies for OM are still unclear as these interventions act on different phases of mucositis and are supported by an insufficient amount of evidence. The updated knowledge on these interventions was reviewed.

Key words: oral mucositis, radiotherapy, chemotherapy, head and neck cancer


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